Endophthalmitis in a patient with disseminated cryptococcosis and AIDS who was treated with itraconazole

D. W. Denning, R. W. Armstrong, M. Fishman, D. A. Stevens*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of presumed cryptococcal endophthalmitis that occurred in a patient with severe disseminated cryptococcosis and AIDS. Multiple small, spherical lesions appeared bilaterally on the surface of the retina 2 weeks after cryptococcal meningitis was diagnosed; the lesions were associated with multiple blind spots, blurred vision, and the perception of flaring of light. Over the next week, many more lesions with adjacent hemorrhages appeared. Therapy with itraconazole over the next 3 months resulted in complete resolution of the lesions. Cryptococcal endophthalmitis is a rare disease. Fewer than 20 cases, including five in patients with AIDS, have previously been reported. None of these patients regained normal vision.

Original languageEnglish
Pages (from-to)1126-1130
Number of pages5
JournalReviews of Infectious Diseases
Volume13
Issue number6
Publication statusPublished - 1 Jan 1991

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