Enhanced visual responses in cat dLGN - Potentiation by priming with excitatory amino acids

C. Rivadulla; K. L. Grieve; J. Cudeiro

Enhanced visual responses in cat dLGN - Potentiation by priming with excitatory amino acids

C. Rivadulla, K. L. Grieve, J. Cudeiro

Research output: Contribution to journal › Article › peer-review

Abstract

SUSTAINED iontophoresis of NMDA potentiated visual responses for minutes after the application in 16 of 38 cells (42%), peaking 3 min after the end of the application and declining to control levels within 12 min. Potentiation was also seen after application of ACPD (36%, n = 14) and AMPA (29%, n = 14), but not after application of ACh (n = 20). ACh also excites dLGN cells, but does not interact with amino acid receptors, and ACh receptors are not directly involved in the transmission of visual information. We suggest that this modulation is a form of visually induced potentiation which permits dynamic modification of the strength of visual information to be relayed to the cortex depending upon the history of previous activity levels.

Original language	English
Pages (from-to)	653-657
Number of pages	4
Journal	NeuroReport
Volume	9
Issue number	4
Publication status	Published - 9 Mar 1998

Keywords

Cat dLGN
Excitatory amino acid receptors
STP
Temporal priming
Visual response modulation

Cite this

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title = "Enhanced visual responses in cat dLGN - Potentiation by priming with excitatory amino acids",

abstract = "SUSTAINED iontophoresis of NMDA potentiated visual responses for minutes after the application in 16 of 38 cells (42%), peaking 3 min after the end of the application and declining to control levels within 12 min. Potentiation was also seen after application of ACPD (36%, n = 14) and AMPA (29%, n = 14), but not after application of ACh (n = 20). ACh also excites dLGN cells, but does not interact with amino acid receptors, and ACh receptors are not directly involved in the transmission of visual information. We suggest that this modulation is a form of visually induced potentiation which permits dynamic modification of the strength of visual information to be relayed to the cortex depending upon the history of previous activity levels.",

keywords = "Cat dLGN, Excitatory amino acid receptors, STP, Temporal priming, Visual response modulation",

author = "C. Rivadulla and Grieve, {K. L.} and J. Cudeiro",

year = "1998",

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pages = "653--657",

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AU - Rivadulla, C.

AU - Grieve, K. L.

AU - Cudeiro, J.

PY - 1998/3/9

Y1 - 1998/3/9

N2 - SUSTAINED iontophoresis of NMDA potentiated visual responses for minutes after the application in 16 of 38 cells (42%), peaking 3 min after the end of the application and declining to control levels within 12 min. Potentiation was also seen after application of ACPD (36%, n = 14) and AMPA (29%, n = 14), but not after application of ACh (n = 20). ACh also excites dLGN cells, but does not interact with amino acid receptors, and ACh receptors are not directly involved in the transmission of visual information. We suggest that this modulation is a form of visually induced potentiation which permits dynamic modification of the strength of visual information to be relayed to the cortex depending upon the history of previous activity levels.

AB - SUSTAINED iontophoresis of NMDA potentiated visual responses for minutes after the application in 16 of 38 cells (42%), peaking 3 min after the end of the application and declining to control levels within 12 min. Potentiation was also seen after application of ACPD (36%, n = 14) and AMPA (29%, n = 14), but not after application of ACh (n = 20). ACh also excites dLGN cells, but does not interact with amino acid receptors, and ACh receptors are not directly involved in the transmission of visual information. We suggest that this modulation is a form of visually induced potentiation which permits dynamic modification of the strength of visual information to be relayed to the cortex depending upon the history of previous activity levels.

KW - Cat dLGN

KW - Excitatory amino acid receptors

KW - STP

KW - Temporal priming

KW - Visual response modulation

M3 - Article

C2 - 9559933

VL - 9

SP - 653

EP - 657

JO - NeuroReport

JF - NeuroReport

IS - 4

ER -

Enhanced visual responses in cat dLGN - Potentiation by priming with excitatory amino acids

Abstract

Keywords

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