Enhancement of Ty transposition at the ADH4 and ADH2 loci in meiotic yeast cells

G. Ribeiro-dos-Santos; A. C G Schenberg; D. C J Gardner; S. G. Oliver

doi:10.1007/s004380050451

Enhancement of Ty transposition at the ADH4 and ADH2 loci in meiotic yeast cells

G. Ribeiro-dos-Santos
, A. C G Schenberg
, D. C J Gardner
, S. G. Oliver

Research output: Contribution to journal › Article › peer-review

Abstract

Genome polymorphism in the yeast Saccharomyces cerevisiae is frequently the result of transposition and recombination events involving Ty elements. The activity of these retrotransposons is closely integrated with the life cycle of the host. Ty transcription is repressed in diploid, but not haploid, cells and is induced by certain stress conditions. We have found that Ty transposition at the ADH4 and ADH2 loci is not only active, but 50-fold more frequent in meiotic yeast than in mitotic cells. These data provide a further example of the success of Ty elements in maximising their own chances of spread and survival while minimising the risks to the host yeast population.

Original language	English
Pages (from-to)	555-561
Number of pages	6
Journal	Molecular and General Genetics
Volume	254
Issue number	5
DOIs	https://doi.org/10.1007/s004380050451
Publication status	Published - 1997

Keywords

Meiosis
Saccharomyces
Starvation
Transposition

Research Beacons, Institutes and Platforms

Manchester Institute of Biotechnology

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10.1007/s004380050451

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title = "Enhancement of Ty transposition at the ADH4 and ADH2 loci in meiotic yeast cells",

abstract = "Genome polymorphism in the yeast Saccharomyces cerevisiae is frequently the result of transposition and recombination events involving Ty elements. The activity of these retrotransposons is closely integrated with the life cycle of the host. Ty transcription is repressed in diploid, but not haploid, cells and is induced by certain stress conditions. We have found that Ty transposition at the ADH4 and ADH2 loci is not only active, but 50-fold more frequent in meiotic yeast than in mitotic cells. These data provide a further example of the success of Ty elements in maximising their own chances of spread and survival while minimising the risks to the host yeast population.",

keywords = "Meiosis, Saccharomyces, Starvation, Transposition",

author = "G. Ribeiro-dos-Santos and Schenberg, \{A. C G\} and Gardner, \{D. C J\} and Oliver, \{S. G.\}",

year = "1997",

doi = "10.1007/s004380050451",

language = "English",

volume = "254",

pages = "555--561",

journal = "Molecular and General Genetics",

publisher = "Springer Nature",

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TY - JOUR

T1 - Enhancement of Ty transposition at the ADH4 and ADH2 loci in meiotic yeast cells

AU - Ribeiro-dos-Santos, G.

AU - Schenberg, A. C G

AU - Gardner, D. C J

AU - Oliver, S. G.

PY - 1997

Y1 - 1997

N2 - Genome polymorphism in the yeast Saccharomyces cerevisiae is frequently the result of transposition and recombination events involving Ty elements. The activity of these retrotransposons is closely integrated with the life cycle of the host. Ty transcription is repressed in diploid, but not haploid, cells and is induced by certain stress conditions. We have found that Ty transposition at the ADH4 and ADH2 loci is not only active, but 50-fold more frequent in meiotic yeast than in mitotic cells. These data provide a further example of the success of Ty elements in maximising their own chances of spread and survival while minimising the risks to the host yeast population.

AB - Genome polymorphism in the yeast Saccharomyces cerevisiae is frequently the result of transposition and recombination events involving Ty elements. The activity of these retrotransposons is closely integrated with the life cycle of the host. Ty transcription is repressed in diploid, but not haploid, cells and is induced by certain stress conditions. We have found that Ty transposition at the ADH4 and ADH2 loci is not only active, but 50-fold more frequent in meiotic yeast than in mitotic cells. These data provide a further example of the success of Ty elements in maximising their own chances of spread and survival while minimising the risks to the host yeast population.

KW - Meiosis

KW - Saccharomyces

KW - Starvation

KW - Transposition

U2 - 10.1007/s004380050451

DO - 10.1007/s004380050451

M3 - Article

C2 - 9197415

VL - 254

SP - 555

EP - 561

JO - Molecular and General Genetics

JF - Molecular and General Genetics

IS - 5

ER -

Enhancement of Ty transposition at the ADH4 and ADH2 loci in meiotic yeast cells

Abstract

Keywords

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