Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine.

Justine Grixti; Steve O’Hagan; Philip Day; Douglas Kell

doi:10.3389/fphar.2017.00155

Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine.

Justine Grixti, Steve O’Hagan, Philip Day, Douglas Kell

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Frontiers in Pharmacology
DOIs	https://doi.org/10.3389/fphar.2017.00155
Publication status	Published - 27 Mar 2017

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10.3389/fphar.2017.00155Licence: CC BY

Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals
Scrutton, N. (PI), Azapagic, A. (CoI), Balmer, A. (CoI), Barran, P. (CoI), Breitling, R. (CoI), Delneri, D. (CoI), Dixon, N. (CoI), Faulon, J.-L. (CoI), Flitsch, S. (CoI), Goble, C. (CoI), Goodacre, R. (CoI), Hay, S. (CoI), Kell, D. (CoI), Leys, D. (CoI), Lloyd, J. (CoI), Lockyer, N. (CoI), Martin, P. (CoI), Micklefield, J. (CoI), Munro, A. (CoI), Pedrosa Mendes, P. (CoI), Randles, S. (CoI), Salehi Yazdi, F. (CoI), Shapira, P. (CoI), Takano, E. (CoI), Turner, N. (CoI) & Winterburn, J. (CoI)
14/11/14 → 13/05/20
Project: Research

Cite this

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title = "Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine.",

author = "Justine Grixti and Steve O{\textquoteright}Hagan and Philip Day and Douglas Kell",

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day = "27",

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language = "English",

journal = "Frontiers in Pharmacology",

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publisher = "Frontiers Media S. A.",

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Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine. / Grixti, Justine; O’Hagan, Steve; Day, Philip et al.
In: Frontiers in Pharmacology, 27.03.2017.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine.

AU - Grixti, Justine

AU - O’Hagan, Steve

AU - Day, Philip

AU - Kell, Douglas

PY - 2017/3/27

Y1 - 2017/3/27

U2 - 10.3389/fphar.2017.00155

DO - 10.3389/fphar.2017.00155

M3 - Article

SN - 1663-9812

JO - Frontiers in Pharmacology

JF - Frontiers in Pharmacology

ER -

Enhancing drug efficacy and therapeutic index through cheminformatics-based selection of small molecule binary weapons that improve transportermediated targeting: a cytotoxicity system based on gemcitabine.

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Manchester Synthetic Biology Research Centre for Fine and Speciality Chemicals

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