Environmental exposure to air pollution and allergens and peak flow changes

B. G. Higgins, H. C. Francis, C. Yates, C. J. Warburton, A. M. Fletcher, C. A C Pickering, A. A. Woodcock

    Research output: Contribution to journalArticlepeer-review


    Laboratory-based studies have shown that ozone and nitrogen dioxide can potentiate the effect of allergen in sensitized asthmatic subjects, but it is not known whether this interaction is important under natural exposure conditions. Thirty-five subjects with clinical diagnoses of asthma or chronic obstructive pulmonary disease and with a provocative dose causing a 20% fall in forced expiratory volume in one second methacholine
    Original languageEnglish
    Pages (from-to)61-66
    Number of pages5
    JournalEuropean Respiratory Journal
    Issue number1
    Publication statusPublished - 2000


    • Aeroallergens
    • Air pollution
    • Asthma
    • Ozone
    • Peak expiratory flow


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