Episodic memory and learning in patients with chronic schizophrenia

T. M. Rushe, P. W R Woodruff, R. M. Murray, R. G. Morris

    Research output: Contribution to journalArticlepeer-review

    Abstract

    This study explored the pattern of memory functioning in 58 patients with chronic schizophrenia and compared their performance with 53 normal controls. Multiple domains of memory were assessed, including verbal and nonverbal memory span, verbal and non-verbal paired associate learning, verbal and visual long-term memory, spatial and non-spatial conditional associative learning, recognition memory and memory for temporal order. Consistent with previous studies, substantial deficits in long-term memory were observed, with relative preservation of memory span. Memory for temporal order and recognition memory was intact, although significant deficits were observed on the conditional associative learning tasks. There was no evidence of lateralized memory impairment. In these respects, the pattern of memory impairment in schizophrenia is more similar in nature to that found in patients with memory dysfunction following mesiotemporal lobe lesions, rather than that associated with focal frontal lobe damage.
    Original languageEnglish
    Pages (from-to)85-96
    Number of pages11
    JournalSchizophrenia Research
    Volume35
    Issue number1
    DOIs
    Publication statusPublished - 4 Jan 1999

    Keywords

    • Non-verbal memory
    • Schizophrenia
    • Verbal memory

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