Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

U-BIOPRED Study Group

doi:10.1183/13993003.00453-2019

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

U-BIOPRED Study Group

Division of Immunology, Immunity to Infection and Respiratory Medicine

Research output: Contribution to journal › Article › peer-review

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Abstract

Stratification of severe asthma on the basis of bronchial epithelial gene expression identified a subset whose endotype is defined by marked epithelial dysregulation associated with obesity, gastro-oesophageal reflux and proton pump inhibitors.

Original language	English
Article number	1900453
Pages (from-to)	1-7
Number of pages	7
Journal	The European respiratory journal
Volume	53
Issue number	6
Early online date	25 Apr 2019
DOIs	https://doi.org/10.1183/13993003.00453-2019
Publication status	Published - 1 Jun 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1183/13993003.00453-2019

Perotin et al. OGP SA_ERJ 2019Accepted author manuscript, 529 KB

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title = "Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux",

abstract = "Stratification of severe asthma on the basis of bronchial epithelial gene expression identified a subset whose endotype is defined by marked epithelial dysregulation associated with obesity, gastro-oesophageal reflux and proton pump inhibitors.",

author = "\{U-BIOPRED Study Group\} and Jeanne-Marie Perotin and Schofield, \{James P R\} and Wilson, \{Susan J\} and Jonathan Ward and Joost Brandsma and Fabio Strazzeri and Aruna Bansal and Xian Yang and Anthony Rowe and Julie Corfield and Rene Lutter and Shaw, \{Dominick E\} and Bakke, \{Per S\} and Massimo Caruso and Barbro Dahl{\'e}n and Fowler, \{Stephen J\} and Ildik{\'o} Horv{\'a}th and Peter Howarth and Norbert Krug and Paolo Montuschi and Marek Sanak and Thomas Sandstr{\"o}m and Kai Sun and Ioannis Pandis and Charles Auffray and \{De Meulder\}, Bertrand and Diane Lefaudeux and Riley, \{John H\} and Sousa, \{Ana R\} and Sven-Erik Dahlen and Adcock, \{Ian M\} and Chung, \{Kian Fan\} and Sterk, \{Peter J\} and Skipp, \{Paul J\} and Collins, \{Jane E\} and Davies, \{Donna E\} and Ratko Djukanovi{\'c}",

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month = jun,

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doi = "10.1183/13993003.00453-2019",

language = "English",

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journal = "The European respiratory journal",

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T1 - Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

AU - U-BIOPRED Study Group

AU - Perotin, Jeanne-Marie

AU - Schofield, James P R

AU - Wilson, Susan J

AU - Ward, Jonathan

AU - Brandsma, Joost

AU - Strazzeri, Fabio

AU - Bansal, Aruna

AU - Yang, Xian

AU - Rowe, Anthony

AU - Corfield, Julie

AU - Lutter, Rene

AU - Shaw, Dominick E

AU - Bakke, Per S

AU - Caruso, Massimo

AU - Dahlén, Barbro

AU - Fowler, Stephen J

AU - Horváth, Ildikó

AU - Howarth, Peter

AU - Krug, Norbert

AU - Montuschi, Paolo

AU - Sanak, Marek

AU - Sandström, Thomas

AU - Sun, Kai

AU - Pandis, Ioannis

AU - Auffray, Charles

AU - De Meulder, Bertrand

AU - Lefaudeux, Diane

AU - Riley, John H

AU - Sousa, Ana R

AU - Dahlen, Sven-Erik

AU - Adcock, Ian M

AU - Chung, Kian Fan

AU - Sterk, Peter J

AU - Skipp, Paul J

AU - Collins, Jane E

AU - Davies, Donna E

AU - Djukanović, Ratko

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Stratification of severe asthma on the basis of bronchial epithelial gene expression identified a subset whose endotype is defined by marked epithelial dysregulation associated with obesity, gastro-oesophageal reflux and proton pump inhibitors.

AB - Stratification of severe asthma on the basis of bronchial epithelial gene expression identified a subset whose endotype is defined by marked epithelial dysregulation associated with obesity, gastro-oesophageal reflux and proton pump inhibitors.

UR - https://www.scopus.com/pages/publications/85069236701

U2 - 10.1183/13993003.00453-2019

DO - 10.1183/13993003.00453-2019

M3 - Article

C2 - 31023846

SN - 0903-1936

VL - 53

SP - 1

EP - 7

JO - The European respiratory journal

JF - The European respiratory journal

IS - 6

M1 - 1900453

ER -

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

Abstract

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