EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria

Désirée Van Der Heijde, Annette H M Van Der Helm-Van Mil, Daniel Aletaha, Clifton O. Bingham, Gerd R. Burmester, Maxime Dougados, Paul Emery, David Felson, Rachel Knevel, Tore K. Kvien, Robert B M Landewé, Cédric Lukas, Iain McInnes, Alan J. Silman, Josef S. Smolen, Ewa Stanislawska-Biernat, Angela Zink, Bernard Combe

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The aim of this report was to propose a definition for erosive disease in the context of inflammatory arthritis in light of the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) rheumatoid arthritis (RA) criteria for use in clinical practice and studies. A EULAR task force was formed including 16 rheumatologists and one rheumatology fellow. The process was both evidence based and consensus based, and included, between March 2010 and April 2012, analyses of data from two cohorts, two face-to-face meetings, one online voting and one teleconference. The Leiden Early Arthritis Cohort and the French ESPOIR cohort were used for the evidence-based part. The outcome measures, which were initiation of methotrexate therapy, or any disease-modifying antirheumatic drug therapy within the first year of disease and arthritis persistency over 5 years, were studied with the aim to give the best definition of erosive disease. A decision was made to select a definition with a high specificity and focus on patients who did not otherwise fulfil the 2010 ACR/EULAR RA criteria (
    Original languageEnglish
    Pages (from-to)479-481
    Number of pages2
    JournalAnnals of the rheumatic diseases
    Volume72
    Issue number4
    DOIs
    Publication statusPublished - Apr 2013

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