European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors

L. Poller; M. Keown; N. Chauhan; A. M H P Van Den Besselaar; A. Tripodi; C. Shiach; J. Jespersen; J. Conard; D. Dias; N. Egberg; J. A. Iriarte; I. Kontopoulou-Griva; B. Otridge

European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors

L. Poller, M. Keown, N. Chauhan, A. M H P Van Den Besselaar, A. Tripodi, C. Shiach, J. Jespersen, J. Conard, D. Dias, N. Egberg, J. A. Iriarte, I. Kontopoulou-Griva, B. Otridge

Research output: Contribution to journal › Article › peer-review

Abstract

A procedure for using citrated fresh plasmas for International Sensitivity Index (ISI) calibration of two types of whole blood point-of-care test (POCT) prothrombin time (PT) monitor systems has been assessed in a multicentre study. The CoaguChek Mini and TAS PT-NC systems gave higher ISI with whole blood samples than with fresh plasma calibrations. However, there was good agreement between whole blood and fresh plasma monitor system International Normalised Ratio (INR) and the reference INR of target samples. Reliable INR can therefore be obtained with both whole blood and plasma samples on these two POCT systems based on their respective ISI. With the CoaguChek Mini system, the plasma calibration ISI can also be used to derive reliable INR with whole blood PT results. This was not possible with the TAS PT-NC system.

Original language	English
Pages (from-to)	859-866
Number of pages	7
Journal	Thrombosis and Haemostasis
Volume	87
Issue number	5
Publication status	Published - 2002

Keywords

International Normalised Ratio
Multicentre ISI
Plasma calibrations
POCT monitors
Prothrombin time

Cite this

Poller, L., Keown, M., Chauhan, N., Van Den Besselaar, A. M. H. P., Tripodi, A., Shiach, C., Jespersen, J., Conard, J., Dias, D., Egberg, N., Iriarte, J. A., Kontopoulou-Griva, I., & Otridge, B. (2002). European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors. Thrombosis and Haemostasis, 87(5), 859-866.

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title = "European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors",

abstract = "A procedure for using citrated fresh plasmas for International Sensitivity Index (ISI) calibration of two types of whole blood point-of-care test (POCT) prothrombin time (PT) monitor systems has been assessed in a multicentre study. The CoaguChek Mini and TAS PT-NC systems gave higher ISI with whole blood samples than with fresh plasma calibrations. However, there was good agreement between whole blood and fresh plasma monitor system International Normalised Ratio (INR) and the reference INR of target samples. Reliable INR can therefore be obtained with both whole blood and plasma samples on these two POCT systems based on their respective ISI. With the CoaguChek Mini system, the plasma calibration ISI can also be used to derive reliable INR with whole blood PT results. This was not possible with the TAS PT-NC system.",

keywords = "International Normalised Ratio, Multicentre ISI, Plasma calibrations, POCT monitors, Prothrombin time",

author = "L. Poller and M. Keown and N. Chauhan and {Van Den Besselaar}, {A. M H P} and A. Tripodi and C. Shiach and J. Jespersen and J. Conard and D. Dias and N. Egberg and Iriarte, {J. A.} and I. Kontopoulou-Griva and B. Otridge",

year = "2002",

language = "English",

volume = "87",

pages = "859--866",

journal = "Thrombosis and Haemostasis",

publisher = "Schattauer Verlag",

number = "5",

}

Poller, L, Keown, M, Chauhan, N, Van Den Besselaar, AMHP, Tripodi, A, Shiach, C, Jespersen, J, Conard, J, Dias, D, Egberg, N, Iriarte, JA, Kontopoulou-Griva, I & Otridge, B 2002, 'European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors', Thrombosis and Haemostasis, vol. 87, no. 5, pp. 859-866.

European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors. / Poller, L.; Keown, M.; Chauhan, N. et al.
In: Thrombosis and Haemostasis, Vol. 87, No. 5, 2002, p. 859-866.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors

AU - Poller, L.

AU - Keown, M.

AU - Chauhan, N.

AU - Van Den Besselaar, A. M H P

AU - Tripodi, A.

AU - Shiach, C.

AU - Jespersen, J.

AU - Conard, J.

AU - Dias, D.

AU - Egberg, N.

AU - Iriarte, J. A.

AU - Kontopoulou-Griva, I.

AU - Otridge, B.

PY - 2002

Y1 - 2002

N2 - A procedure for using citrated fresh plasmas for International Sensitivity Index (ISI) calibration of two types of whole blood point-of-care test (POCT) prothrombin time (PT) monitor systems has been assessed in a multicentre study. The CoaguChek Mini and TAS PT-NC systems gave higher ISI with whole blood samples than with fresh plasma calibrations. However, there was good agreement between whole blood and fresh plasma monitor system International Normalised Ratio (INR) and the reference INR of target samples. Reliable INR can therefore be obtained with both whole blood and plasma samples on these two POCT systems based on their respective ISI. With the CoaguChek Mini system, the plasma calibration ISI can also be used to derive reliable INR with whole blood PT results. This was not possible with the TAS PT-NC system.

AB - A procedure for using citrated fresh plasmas for International Sensitivity Index (ISI) calibration of two types of whole blood point-of-care test (POCT) prothrombin time (PT) monitor systems has been assessed in a multicentre study. The CoaguChek Mini and TAS PT-NC systems gave higher ISI with whole blood samples than with fresh plasma calibrations. However, there was good agreement between whole blood and fresh plasma monitor system International Normalised Ratio (INR) and the reference INR of target samples. Reliable INR can therefore be obtained with both whole blood and plasma samples on these two POCT systems based on their respective ISI. With the CoaguChek Mini system, the plasma calibration ISI can also be used to derive reliable INR with whole blood PT results. This was not possible with the TAS PT-NC system.

KW - International Normalised Ratio

KW - Multicentre ISI

KW - Plasma calibrations

KW - POCT monitors

KW - Prothrombin time

M3 - Article

C2 - 12038790

VL - 87

SP - 859

EP - 866

JO - Thrombosis and Haemostasis

JF - Thrombosis and Haemostasis

IS - 5

ER -

European concerted action on anticoagulation: Comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors

Abstract

Keywords

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