TY - JOUR
T1 - European consensus conference on diagnosis and treatment of germ cell cancer
T2 - a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I
AU - Krege, Susanne
AU - Beyer, Jörg
AU - Souchon, Rainer
AU - Albers, Peter
AU - Albrecht, Walter
AU - Algaba, Ferran
AU - Bamberg, Michael
AU - Bodrogi, István
AU - Bokemeyer, Carsten
AU - Cavallin-Ståhl, Eva
AU - Classen, Johannes
AU - Clemm, Christoph
AU - Cohn-Cedermark, Gabriella
AU - Culine, Stéphane
AU - Daugaard, Gedske
AU - De Mulder, Pieter H M
AU - De Santis, Maria
AU - de Wit, Maike
AU - de Wit, Ronald
AU - Derigs, Hans Günter
AU - Dieckmann, Klaus-Peter
AU - Dieing, Annette
AU - Droz, Jean-Pierre
AU - Fenner, Martin
AU - Fizazi, Karim
AU - Flechon, Aude
AU - Fosså, Sophie D
AU - del Muro, Xavier Garcia
AU - Gauler, Thomas
AU - Geczi, Lajos
AU - Gerl, Arthur
AU - Germa-Lluch, Jose Ramon
AU - Gillessen, Silke
AU - Hartmann, Jörg T
AU - Hartmann, Michael
AU - Heidenreich, Axel
AU - Hoeltl, Wolfgang
AU - Horwich, Alan
AU - Huddart, Robert
AU - Jewett, Michael
AU - Joffe, Johnathan
AU - Jones, William G
AU - Kisbenedek, László
AU - Klepp, Olbjørn
AU - Kliesch, Sabine
AU - Koehrmann, Kai Uwe
AU - Kollmannsberger, Christian
AU - Kuczyk, Markus
AU - Laguna, Pilar
AU - Galvis, Oscar Leiva
PY - 2008/3
Y1 - 2008/3
N2 - OBJECTIVES: The first consensus report presented by the European Germ Cell Cancer Consensus Group (EGCCCG) in the year 2004 has found widespread approval by many colleagues throughout the world. In November 2006, the group met a second time under the auspices of the Department of Urology of the Amsterdam Medical Center, Amsterdam, The Netherlands.METHODS: Medical oncologists, urological surgeons, radiation oncologists as well as pathologists from several European countries reviewed and discussed the data that had emerged since the 2002 conference, and incorporated the new data into updated and revised guidelines. As for the first meeting, the methodology of evidence-based medicine (EBM) was applied. The results of the discussion were compiled by the writing committee. All participants have agreed to this final update.RESULTS: The first part of the consensus paper describes the clinical presentation of the primary tumor, its treatment, the importance and treatment of testicular intraepithelial neoplasia (TIN), histological classification, staging and prognostic factors, and treatment of stage I seminoma and non-seminoma.CONCLUSIONS: Whereas the vast majority of the recommendations made in 2004 remain valid 3 yr later, refinements in the treatment of early- and advanced-stage testicular cancer have emerged from clinical trials. Despite technical improvements, expert clinical skills will continue to be one of the major determinants for the prognosis of patients with germ cell cancer. In addition, the particular needs of testicular cancer survivors have been acknowledged.
AB - OBJECTIVES: The first consensus report presented by the European Germ Cell Cancer Consensus Group (EGCCCG) in the year 2004 has found widespread approval by many colleagues throughout the world. In November 2006, the group met a second time under the auspices of the Department of Urology of the Amsterdam Medical Center, Amsterdam, The Netherlands.METHODS: Medical oncologists, urological surgeons, radiation oncologists as well as pathologists from several European countries reviewed and discussed the data that had emerged since the 2002 conference, and incorporated the new data into updated and revised guidelines. As for the first meeting, the methodology of evidence-based medicine (EBM) was applied. The results of the discussion were compiled by the writing committee. All participants have agreed to this final update.RESULTS: The first part of the consensus paper describes the clinical presentation of the primary tumor, its treatment, the importance and treatment of testicular intraepithelial neoplasia (TIN), histological classification, staging and prognostic factors, and treatment of stage I seminoma and non-seminoma.CONCLUSIONS: Whereas the vast majority of the recommendations made in 2004 remain valid 3 yr later, refinements in the treatment of early- and advanced-stage testicular cancer have emerged from clinical trials. Despite technical improvements, expert clinical skills will continue to be one of the major determinants for the prognosis of patients with germ cell cancer. In addition, the particular needs of testicular cancer survivors have been acknowledged.
KW - Biopsy
KW - Combined Modality Therapy/methods
KW - Consensus
KW - Consensus Development Conferences as Topic
KW - Europe
KW - Humans
KW - Male
KW - Neoplasm Staging/methods
KW - Neoplasms, Germ Cell and Embryonal/diagnosis
KW - Practice Guidelines as Topic
KW - Prognosis
KW - Societies, Medical
KW - Testicular Neoplasms/diagnosis
UR - https://www.scopus.com/pages/publications/38949169584
U2 - 10.1016/j.eururo.2007.12.024
DO - 10.1016/j.eururo.2007.12.024
M3 - Review article
C2 - 18191324
SN - 0302-2838
VL - 53
SP - 478
EP - 496
JO - European Urology
JF - European Urology
IS - 3
ER -