Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells

Lee Turnpenny; Cosma M. Spalluto; Rebecca M. Perrett; Marie O'Shea; Karen Piper Hanley; Iain T. Cameron; David I. Wilson; Neil A. Hanley

doi:10.1634/stemcells.2005-0255

Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells

Lee Turnpenny, Cosma M. Spalluto, Rebecca M. Perrett, Marie O'Shea, Karen Piper Hanley, Iain T. Cameron, David I. Wilson, Neil A. Hanley

Research output: Contribution to journal › Article › peer-review

Abstract

The realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations. ©AlphaMed Press.

Original language	English
Pages (from-to)	212-220
Number of pages	8
Journal	Stem Cells
Issue number	2
DOIs	https://doi.org/10.1634/stemcells.2005-0255 https://doi.org/10.1634/stemcells.2005-0255
Publication status	Published - Feb 2006

Keywords

Embryo
Embryonic germ cell
Gonad
Human
Primordial germ cell
Stem cell

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http://stemcells.alphamedpress.org/cgi/reprint/24/2/212.pdf

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AU - Hanley, Karen Piper

AU - Cameron, Iain T.

AU - Wilson, David I.

AU - Hanley, Neil A.

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AB - The realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations. ©AlphaMed Press.

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Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells

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Keywords

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