Evidence of recombination between divergent hepatitis E viruses

Hélène Van Cuyck, Jun Fan, David L. Robertson, Pierre Roques

    Research output: Contribution to journalArticlepeer-review


    Phylogenetic and recombination analysis was performed on 32 complete hepatitis E virus (HEV) genomes from infected humans and pigs. For the first time, evidence for recombination between divergent HEV strains was obtained, with at least two strains being found to have discordant phylogenetic relationships consistent with the occurrence of intragenotype recombination. This finding confirms that humans can be dually infected with divergent HEV strains and has implications for the emergence and evolution of new HEV epidemics. Copyright © 2005, American Society for Microbiology. All Rights Reserved.
    Original languageEnglish
    Pages (from-to)9306-9314
    Number of pages8
    JournalJournal of virology
    Issue number14
    Publication statusPublished - Jul 2005


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