Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs

Sizheng Steven Zhao; Stephanie R Harrison; Ben Thompson; Max Yates; Joe Eddison; Antoni Chan; Nick Clarke; Nadia Corp; Charlotte Davis; Lambert Felix; Kalveer Flora; William J Gregory; Gareth T Jones; Christopher A Lamb; Helena Marzo-Ortega; Daniel J Murphy; Harry Petrushkin; Virinderjit Sandhu; Raj Sengupta; Stefan Siebert; Danielle A Van Der Windt; Dale Webb; Zenas Z N Yiu; Karl Gaffney

doi:10.1093/rheumatology/keaf090

Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs

Sizheng Steven Zhao
, Stephanie R Harrison
, Ben Thompson
, Max Yates
, Joe Eddison
, Antoni Chan
, Nick Clarke
, Nadia Corp
, Charlotte Davis
, Lambert Felix
, Kalveer Flora
, William J Gregory
, Gareth T Jones
, Christopher A Lamb
, Helena Marzo-Ortega
, Daniel J Murphy
, Harry Petrushkin
, Virinderjit Sandhu
, Raj Sengupta
, Stefan Siebert

Danielle A Van Der Windt, Dale Webb, Zenas Z N Yiu, Karl Gaffney

Research output: Contribution to journal › Article › peer-review

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Original language	English
Article number	keaf090
Journal	Rheumatology (Oxford, England)
Early online date	9 Apr 2025
DOIs	https://doi.org/10.1093/rheumatology/keaf090
Publication status	E-pub ahead of print - 9 Apr 2025

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10.1093/rheumatology/keaf090

axSpA guideline 2025 executive sum R2_cleanAccepted author manuscript, 74.9 KBLicence: CC BY

NIHR Manchester Biomedical Research Centre
Bruce, I. (PI), Lord, G. (CoI), Lennon, R. (CoI), Black, G. (CoI), Wedge, D. (CoI), Morris, A. (CoI), Hussell, T. (CoI), Sharrocks, A. (CoI), Stivaros, S. (CoI), Buch, M. (CoI), Gough, J. (CoI), Kostarelos, K. (CoI), Thistlethwaite, F. (CoI), Kadler, K. (CoI), Barton, A. (CoI), Hyrich, K. (CoI), Mcbeth, J. (CoI), O'Neill, T. (CoI), Vestbo, J. (CoI), Simpson, A. (CoI), Singh, S. (CoI), Smith, J. (CoI), Felton, T. (CoI), Murray, C. (CoI), Griffiths, C. (CoI), Cullum, N. (CoI), Rhodes, L. (CoI), Warren, R. (CoI), Paus, R. (CoI), Dumville, J. (CoI), Viros Usandizaga, A. (CoI), Keavney, B. (CoI), Tomaszewski, M. (CoI), Allan, S. (CoI), Body, R. (CoI), Cartwright, E. (CoI), Heagerty, A. (CoI), Kalra, P. (CoI), Miller, C. (CoI), Rutter, M. (CoI), Smith, C. (CoI), Trafford, A. (CoI), Evans, D. (CoI), Davidson, E. (CoI), Crosbie, P. (CoI), Harvie, M. (CoI), Howell, S. (CoI), Renehan, A. (CoI), Dive, C. (CoI), Blackhall, F. (CoI), Landers, D. (CoI), Krebs, M. (CoI), Cook, N. (CoI), Clarke, R. (CoI), Taylor, S. (CoI), Jorgensen, C. (CoI), Lorigan, P. (CoI), Jayson, G. (CoI), Valle, J. (CoI), Mccabe, M. (CoI), Armstrong, A. (CoI), Freitas, A. (CoI), Illidge, T. (CoI), Choudhury, A. (CoI), Hoskin, P. (CoI), West, C. (CoI), Van Herk, M. (CoI), Faivre-Finn, C. (CoI), Bristow, R. (CoI), Kirkby, K. (CoI), Birtle, A. (CoI), Mackay, R. (CoI), Radford, J. (CoI), Linton, K. (CoI), Higham, C. (CoI), Munro, K. (CoI), Plack, C. (CoI), Arden Armitage, C. (CoI), Bruce, I. (CoI), Moore, D. (CoI), Saunders, G. (CoI), Stone, M. (CoI), Haddock, G. (CoI), Lewis, S. (CoI), Elliott, R. (CoI), Green, J. (CoI), Lovell, K. (CoI), Morrison, A. (CoI), Shaw, J. (CoI), Bucci, S. (CoI), Ainsworth, J. (CoI), Webb, R. (CoI), Newman, W. (CoI), Banka, S. (CoI), Clayton-Smith, J. (CoI), Payne, K. (CoI), Moldovan, R. (CoI), Wynn, R. (CoI) & Jones, S. (CoI)
1/12/22 → 30/11/27
Project: Research
Centre for Epidemiology Versus Arthritis.
Dixon, W. (PI), Bruce, I. (CoI), Felson, D. (CoI), Hyrich, K. (CoI), Lunt, M. (CoI), Mcbeth, J. (CoI), Mcdonagh, J. (CoI), O'Neill, T. (CoI), Sergeant, J. (CoI), Verstappen, S. (CoI) & Serafimova, I. (Support team)
1/08/18 → 31/07/26
Project: Research

Cite this

Zhao, S. S., Harrison, S. R., Thompson, B., Yates, M., Eddison, J., Chan, A., Clarke, N., Corp, N., Davis, C., Felix, L., Flora, K., Gregory, W. J., Jones, G. T., Lamb, C. A., Marzo-Ortega, H., Murphy, D. J., Petrushkin, H., Sandhu, V., Sengupta, R., ... Gaffney, K. (2025). Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs. Rheumatology (Oxford, England), Article keaf090. Advance online publication. https://doi.org/10.1093/rheumatology/keaf090

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title = "Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs",

author = "Zhao, \{Sizheng Steven\} and Harrison, \{Stephanie R\} and Ben Thompson and Max Yates and Joe Eddison and Antoni Chan and Nick Clarke and Nadia Corp and Charlotte Davis and Lambert Felix and Kalveer Flora and Gregory, \{William J\} and Jones, \{Gareth T\} and Lamb, \{Christopher A\} and Helena Marzo-Ortega and Murphy, \{Daniel J\} and Harry Petrushkin and Virinderjit Sandhu and Raj Sengupta and Stefan Siebert and \{Van Der Windt\}, \{Danielle A\} and Dale Webb and Yiu, \{Zenas Z N\} and Karl Gaffney",

year = "2025",

month = apr,

day = "9",

doi = "10.1093/rheumatology/keaf090",

language = "English",

journal = "Rheumatology (Oxford, England)",

issn = "1462-0324",

publisher = "Oxford University Press",

}

Zhao, SS, Harrison, SR, Thompson, B, Yates, M, Eddison, J, Chan, A, Clarke, N, Corp, N, Davis, C, Felix, L, Flora, K, Gregory, WJ, Jones, GT, Lamb, CA, Marzo-Ortega, H, Murphy, DJ, Petrushkin, H, Sandhu, V, Sengupta, R, Siebert, S, Van Der Windt, DA, Webb, D, Yiu, ZZN & Gaffney, K 2025, 'Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs', Rheumatology (Oxford, England). https://doi.org/10.1093/rheumatology/keaf090

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T2 - The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs

AU - Zhao, Sizheng Steven

AU - Harrison, Stephanie R

AU - Thompson, Ben

AU - Yates, Max

AU - Eddison, Joe

AU - Chan, Antoni

AU - Clarke, Nick

AU - Corp, Nadia

AU - Davis, Charlotte

AU - Felix, Lambert

AU - Flora, Kalveer

AU - Gregory, William J

AU - Jones, Gareth T

AU - Lamb, Christopher A

AU - Marzo-Ortega, Helena

AU - Murphy, Daniel J

AU - Petrushkin, Harry

AU - Sandhu, Virinderjit

AU - Sengupta, Raj

AU - Siebert, Stefan

AU - Van Der Windt, Danielle A

AU - Webb, Dale

AU - Yiu, Zenas Z N

AU - Gaffney, Karl

PY - 2025/4/9

Y1 - 2025/4/9

U2 - 10.1093/rheumatology/keaf090

DO - 10.1093/rheumatology/keaf090

M3 - Article

C2 - 40199508

SN - 1462-0324

JO - Rheumatology (Oxford, England)

JF - Rheumatology (Oxford, England)

M1 - keaf090

ER -

Executive Summary: The 2025 British Society for Rheumatology guideline for the treatment of axial spondyloarthritis with biologic and targeted synthetic DMARDs

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Projects

NIHR Manchester Biomedical Research Centre

Centre for Epidemiology Versus Arthritis.

Cite this