Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia

A. R. Crossman; M. A. Sambrook; A. Jackson

doi:10.1016/0304-3940(80)90176-7

Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia

A. R. Crossman^*, M. A. Sambrook, A. Jackson

^*Corresponding author for this work

University Hospital of South Manchester NHS Foundation Trust

Research output: Contribution to journal › Article › peer-review

Abstract

Hemiballismus was produced experimentally in the baboon by injection of the gamma-aminobutyric acid (GABA) antagonist picrotoxin into the globus pallidus/subthalamic nucleus of the conscious animal. The abnormal movements appeared in the limbs contralateral to the injected side and were of a character similar to those reported following lesions of the subthalamic nucleus.

Original language	English
Pages (from-to)	369-372
Number of pages	4
Journal	Neuroscience letters
Volume	20
Issue number	3
DOIs	https://doi.org/10.1016/0304-3940(80)90176-7
Publication status	Published - 1 Jan 1980

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10.1016/0304-3940(80)90176-7

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abstract = "Hemiballismus was produced experimentally in the baboon by injection of the gamma-aminobutyric acid (GABA) antagonist picrotoxin into the globus pallidus/subthalamic nucleus of the conscious animal. The abnormal movements appeared in the limbs contralateral to the injected side and were of a character similar to those reported following lesions of the subthalamic nucleus.",

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AU - Jackson, A.

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AB - Hemiballismus was produced experimentally in the baboon by injection of the gamma-aminobutyric acid (GABA) antagonist picrotoxin into the globus pallidus/subthalamic nucleus of the conscious animal. The abnormal movements appeared in the limbs contralateral to the injected side and were of a character similar to those reported following lesions of the subthalamic nucleus.

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Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia

Abstract

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