Exploring patterns of response across the lifespan: The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study

Emma Green; Holly Bennett; Carol Brayne; Lorraine K. Tyler; Edward T. Bullmore; Andrew C. Calder; Rhodri Cusack; Tim Dalgleish; John Duncan; Richard N. Henson; William D. Marslen-Wilson; James B. Rowe; Meredith A. Shafto; Karen Campbell; Teresa Cheung; Simon Davis; Linda Geerligs; Rogier Kievit; Anna McCarrey; Abdur Mustafa; Darren Price; David Samu; Jason R. Taylor; Matthias Treder; Kamen Tsvetanov; Janna Van Belle; Nitin Williams; Lauren Bates; Tina Emery; Sharon Erzinçlioglu; Andrew Gadie; Sofia Gerbase; Stanimira Georgieva; Claire Hanley; Beth Parkin; David Troy; Tibor Auer; Marta Correia; Lu Gao; Rafael Henriques; Jodie Allen; Gillian Amery; Liana Amunts; Anne Barcroft; Amanda Castle; Cheryl Dias; Jonathan Dowrick; Melissa Fair; Hayley Fisher; Anna Goulding; Cam-CAN

doi:10.1186/s12889-018-5663-7

Exploring patterns of response across the lifespan: The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study

Emma Green^*, Holly Bennett, Carol Brayne, Lorraine K. Tyler, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Richard N. Henson, William D. Marslen-Wilson, James B. Rowe, Meredith A. Shafto, Karen Campbell, Teresa Cheung, Simon Davis, Linda Geerligs, Rogier Kievit, Anna McCarrey, Abdur MustafaDarren Price, David Samu, Jason R. Taylor, Matthias Treder, Kamen Tsvetanov, Janna Van Belle, Nitin Williams, Lauren Bates, Tina Emery, Sharon Erzinçlioglu, Andrew Gadie, Sofia Gerbase, Stanimira Georgieva, Claire Hanley, Beth Parkin, David Troy, Tibor Auer, Marta Correia, Lu Gao, Rafael Henriques, Jodie Allen, Gillian Amery, Liana Amunts, Anne Barcroft, Amanda Castle, Cheryl Dias, Jonathan Dowrick, Melissa Fair, Hayley Fisher, Anna Goulding, Cam-CAN

^*Corresponding author for this work

Division of Neuroscience

University of Cambridge

Research output: Contribution to journal › Article › peer-review

Abstract

Background: With declining rates of participation in epidemiological studies there is an important need to attempt to understand what factors might affect response. This study examines the pattern of response at different adult ages within a contemporary cross-sectional population-based cohort, the Cambridge Centre for Ageing and Neuroscience (Cam-CAN). Methods: Using logistic regression, we investigated associations between age, gender and Townsend deprivation level for both participants and non-participants. Weighted estimates of the odds ratios with confidence intervals for each demographic characteristic were calculated. Reasons given for refusal were grouped into three broad categories: 'active', 'passive' and illness preventing interview. Results: An association of age and participation was found, with individuals in middle age groups more likely to participate (age group 48-57 OR: 1.8, 95% CI: 1.5-2.2 and age group 58-67 OR: 2.1, 95% CI: 1.7-2.4). Overall, there was no difference in participation between men and women. An association with deprivation was found, with those living in the most deprived areas being the least willing to participate (fifth quintile OR: 0.6, 95% CI: 0.5-0.7). An interaction between age and gender was found whereby younger women and older men were more likely to agree to participate (p = 0.01). Conclusion: Our findings highlight some of the factors affecting recruitment into epidemiological studies in the UK and suggest that targeted age-specific recruitment strategies might be needed to increase participation rates in future cohort investigations.

Original language	English
Article number	760
Journal	BMC Public Health
Volume	18
Issue number	1
Early online date	19 Jun 2018
DOIs	https://doi.org/10.1186/s12889-018-5663-7
Publication status	Published - 2018

Keywords

Ageing
Cognition
Epidemiological study
Lifespan
Neuroscience
Non-participation

Research Beacons, Institutes and Platforms

Manchester Institute for Collaborative Research on Ageing

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Green, E., Bennett, H., Brayne, C., Tyler, L. K., Bullmore, E. T., Calder, A. C., Cusack, R., Dalgleish, T., Duncan, J., Henson, R. N., Marslen-Wilson, W. D., Rowe, J. B., Shafto, M. A., Campbell, K., Cheung, T., Davis, S., Geerligs, L., Kievit, R., McCarrey, A., ... Cam-CAN (2018). Exploring patterns of response across the lifespan: The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study. BMC Public Health, 18(1), Article 760. https://doi.org/10.1186/s12889-018-5663-7

@article{b6b8879e72c44ed8966151264aa29821,

title = "Exploring patterns of response across the lifespan: The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study",

abstract = "Background: With declining rates of participation in epidemiological studies there is an important need to attempt to understand what factors might affect response. This study examines the pattern of response at different adult ages within a contemporary cross-sectional population-based cohort, the Cambridge Centre for Ageing and Neuroscience (Cam-CAN). Methods: Using logistic regression, we investigated associations between age, gender and Townsend deprivation level for both participants and non-participants. Weighted estimates of the odds ratios with confidence intervals for each demographic characteristic were calculated. Reasons given for refusal were grouped into three broad categories: 'active', 'passive' and illness preventing interview. Results: An association of age and participation was found, with individuals in middle age groups more likely to participate (age group 48-57 OR: 1.8, 95% CI: 1.5-2.2 and age group 58-67 OR: 2.1, 95% CI: 1.7-2.4). Overall, there was no difference in participation between men and women. An association with deprivation was found, with those living in the most deprived areas being the least willing to participate (fifth quintile OR: 0.6, 95% CI: 0.5-0.7). An interaction between age and gender was found whereby younger women and older men were more likely to agree to participate (p = 0.01). Conclusion: Our findings highlight some of the factors affecting recruitment into epidemiological studies in the UK and suggest that targeted age-specific recruitment strategies might be needed to increase participation rates in future cohort investigations.",

keywords = "Ageing, Cognition, Epidemiological study, Lifespan, Neuroscience, Non-participation",

author = "Emma Green and Holly Bennett and Carol Brayne and Tyler, {Lorraine K.} and Bullmore, {Edward T.} and Calder, {Andrew C.} and Rhodri Cusack and Tim Dalgleish and John Duncan and Henson, {Richard N.} and Marslen-Wilson, {William D.} and Rowe, {James B.} and Shafto, {Meredith A.} and Karen Campbell and Teresa Cheung and Simon Davis and Linda Geerligs and Rogier Kievit and Anna McCarrey and Abdur Mustafa and Darren Price and David Samu and Taylor, {Jason R.} and Matthias Treder and Kamen Tsvetanov and {Van Belle}, Janna and Nitin Williams and Lauren Bates and Tina Emery and Sharon Erzin{\c c}lioglu and Andrew Gadie and Sofia Gerbase and Stanimira Georgieva and Claire Hanley and Beth Parkin and David Troy and Tibor Auer and Marta Correia and Lu Gao and Rafael Henriques and Jodie Allen and Gillian Amery and Liana Amunts and Anne Barcroft and Amanda Castle and Cheryl Dias and Jonathan Dowrick and Melissa Fair and Hayley Fisher and Anna Goulding and Cam-CAN",

year = "2018",

doi = "10.1186/s12889-018-5663-7",

language = "English",

volume = "18",

journal = "BMC Public Health",

issn = "1471-2458",

publisher = "Springer Nature",

number = "1",

}

Green, E, Bennett, H, Brayne, C, Tyler, LK, Bullmore, ET, Calder, AC, Cusack, R, Dalgleish, T, Duncan, J, Henson, RN, Marslen-Wilson, WD, Rowe, JB, Shafto, MA, Campbell, K, Cheung, T, Davis, S, Geerligs, L, Kievit, R, McCarrey, A, Mustafa, A, Price, D, Samu, D, Taylor, JR, Treder, M, Tsvetanov, K, Van Belle, J, Williams, N, Bates, L, Emery, T, Erzinçlioglu, S, Gadie, A, Gerbase, S, Georgieva, S, Hanley, C, Parkin, B, Troy, D, Auer, T, Correia, M, Gao, L, Henriques, R, Allen, J, Amery, G, Amunts, L, Barcroft, A, Castle, A, Dias, C, Dowrick, J, Fair, M, Fisher, H, Goulding, A & Cam-CAN 2018, 'Exploring patterns of response across the lifespan: The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study', BMC Public Health, vol. 18, no. 1, 760. https://doi.org/10.1186/s12889-018-5663-7

TY - JOUR

T1 - Exploring patterns of response across the lifespan

T2 - The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study

AU - Green, Emma

AU - Bennett, Holly

AU - Brayne, Carol

AU - Tyler, Lorraine K.

AU - Bullmore, Edward T.

AU - Calder, Andrew C.

AU - Cusack, Rhodri

AU - Dalgleish, Tim

AU - Duncan, John

AU - Henson, Richard N.

AU - Marslen-Wilson, William D.

AU - Rowe, James B.

AU - Shafto, Meredith A.

AU - Campbell, Karen

AU - Cheung, Teresa

AU - Davis, Simon

AU - Geerligs, Linda

AU - Kievit, Rogier

AU - McCarrey, Anna

AU - Mustafa, Abdur

AU - Price, Darren

AU - Samu, David

AU - Taylor, Jason R.

AU - Treder, Matthias

AU - Tsvetanov, Kamen

AU - Van Belle, Janna

AU - Williams, Nitin

AU - Bates, Lauren

AU - Emery, Tina

AU - Erzinçlioglu, Sharon

AU - Gadie, Andrew

AU - Gerbase, Sofia

AU - Georgieva, Stanimira

AU - Hanley, Claire

AU - Parkin, Beth

AU - Troy, David

AU - Auer, Tibor

AU - Correia, Marta

AU - Gao, Lu

AU - Henriques, Rafael

AU - Allen, Jodie

AU - Amery, Gillian

AU - Amunts, Liana

AU - Barcroft, Anne

AU - Castle, Amanda

AU - Dias, Cheryl

AU - Dowrick, Jonathan

AU - Fair, Melissa

AU - Fisher, Hayley

AU - Goulding, Anna

AU - Cam-CAN,

PY - 2018

Y1 - 2018

N2 - Background: With declining rates of participation in epidemiological studies there is an important need to attempt to understand what factors might affect response. This study examines the pattern of response at different adult ages within a contemporary cross-sectional population-based cohort, the Cambridge Centre for Ageing and Neuroscience (Cam-CAN). Methods: Using logistic regression, we investigated associations between age, gender and Townsend deprivation level for both participants and non-participants. Weighted estimates of the odds ratios with confidence intervals for each demographic characteristic were calculated. Reasons given for refusal were grouped into three broad categories: 'active', 'passive' and illness preventing interview. Results: An association of age and participation was found, with individuals in middle age groups more likely to participate (age group 48-57 OR: 1.8, 95% CI: 1.5-2.2 and age group 58-67 OR: 2.1, 95% CI: 1.7-2.4). Overall, there was no difference in participation between men and women. An association with deprivation was found, with those living in the most deprived areas being the least willing to participate (fifth quintile OR: 0.6, 95% CI: 0.5-0.7). An interaction between age and gender was found whereby younger women and older men were more likely to agree to participate (p = 0.01). Conclusion: Our findings highlight some of the factors affecting recruitment into epidemiological studies in the UK and suggest that targeted age-specific recruitment strategies might be needed to increase participation rates in future cohort investigations.

AB - Background: With declining rates of participation in epidemiological studies there is an important need to attempt to understand what factors might affect response. This study examines the pattern of response at different adult ages within a contemporary cross-sectional population-based cohort, the Cambridge Centre for Ageing and Neuroscience (Cam-CAN). Methods: Using logistic regression, we investigated associations between age, gender and Townsend deprivation level for both participants and non-participants. Weighted estimates of the odds ratios with confidence intervals for each demographic characteristic were calculated. Reasons given for refusal were grouped into three broad categories: 'active', 'passive' and illness preventing interview. Results: An association of age and participation was found, with individuals in middle age groups more likely to participate (age group 48-57 OR: 1.8, 95% CI: 1.5-2.2 and age group 58-67 OR: 2.1, 95% CI: 1.7-2.4). Overall, there was no difference in participation between men and women. An association with deprivation was found, with those living in the most deprived areas being the least willing to participate (fifth quintile OR: 0.6, 95% CI: 0.5-0.7). An interaction between age and gender was found whereby younger women and older men were more likely to agree to participate (p = 0.01). Conclusion: Our findings highlight some of the factors affecting recruitment into epidemiological studies in the UK and suggest that targeted age-specific recruitment strategies might be needed to increase participation rates in future cohort investigations.

KW - Ageing

KW - Cognition

KW - Epidemiological study

KW - Lifespan

KW - Neuroscience

KW - Non-participation

UR - http://www.scopus.com/inward/record.url?scp=85048733385&partnerID=8YFLogxK

U2 - 10.1186/s12889-018-5663-7

DO - 10.1186/s12889-018-5663-7

M3 - Article

AN - SCOPUS:85048733385

SN - 1471-2458

VL - 18

JO - BMC Public Health

JF - BMC Public Health

IS - 1

M1 - 760

ER -

Exploring patterns of response across the lifespan: The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study

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Keywords

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