Exploring the role of prolactin in psoriasis

Ewan A. Langan; Christopher E M Griffiths; Ralf Paus

doi:10.1007/s00403-012-1208-6

Exploring the role of prolactin in psoriasis

Ewan A. Langan, Christopher E M Griffiths, Ralf Paus

Research output: Contribution to journal › Article › peer-review

Abstract

Prolactin (PRL) is well recognised for its role(s) in mammary gland development and function. Moreover, its role in skin biology, including the potent regulation of human hair growth, is becoming clearer. Less widely appreciated, however, is the potential role of PRL in the pathobiology of psoriasis. While the relationship between PRL and psoriasis remains enigmatic, several recent publications on the PRL-psoriasis connection have demonstrated a reawakening of interest in this conundrum. We take the occasion of these reports to underscore the importance of dissecting the role(s) of PRL in the aetiopathology of psoriasis, not least since this may help to identify novel hormonal treatment strategies in its management. © 2012 Springer-Verlag.

Original language	English
Pages (from-to)	115-118
Number of pages	3
Journal	Archives of Dermatological Research
Volume	304
Issue number	2
DOIs	https://doi.org/10.1007/s00403-012-1208-6
Publication status	Published - Mar 2012

Keywords

Prolactin
Psoriasis
Skin

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10.1007/s00403-012-1208-6

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title = "Exploring the role of prolactin in psoriasis",

abstract = "Prolactin (PRL) is well recognised for its role(s) in mammary gland development and function. Moreover, its role in skin biology, including the potent regulation of human hair growth, is becoming clearer. Less widely appreciated, however, is the potential role of PRL in the pathobiology of psoriasis. While the relationship between PRL and psoriasis remains enigmatic, several recent publications on the PRL-psoriasis connection have demonstrated a reawakening of interest in this conundrum. We take the occasion of these reports to underscore the importance of dissecting the role(s) of PRL in the aetiopathology of psoriasis, not least since this may help to identify novel hormonal treatment strategies in its management. {\textcopyright} 2012 Springer-Verlag.",

keywords = "Prolactin, Psoriasis, Skin",

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AU - Langan, Ewan A.

AU - Griffiths, Christopher E M

AU - Paus, Ralf

N1 - , Medical Research Council, United Kingdom

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Y1 - 2012/3

N2 - Prolactin (PRL) is well recognised for its role(s) in mammary gland development and function. Moreover, its role in skin biology, including the potent regulation of human hair growth, is becoming clearer. Less widely appreciated, however, is the potential role of PRL in the pathobiology of psoriasis. While the relationship between PRL and psoriasis remains enigmatic, several recent publications on the PRL-psoriasis connection have demonstrated a reawakening of interest in this conundrum. We take the occasion of these reports to underscore the importance of dissecting the role(s) of PRL in the aetiopathology of psoriasis, not least since this may help to identify novel hormonal treatment strategies in its management. © 2012 Springer-Verlag.

AB - Prolactin (PRL) is well recognised for its role(s) in mammary gland development and function. Moreover, its role in skin biology, including the potent regulation of human hair growth, is becoming clearer. Less widely appreciated, however, is the potential role of PRL in the pathobiology of psoriasis. While the relationship between PRL and psoriasis remains enigmatic, several recent publications on the PRL-psoriasis connection have demonstrated a reawakening of interest in this conundrum. We take the occasion of these reports to underscore the importance of dissecting the role(s) of PRL in the aetiopathology of psoriasis, not least since this may help to identify novel hormonal treatment strategies in its management. © 2012 Springer-Verlag.

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KW - Psoriasis

KW - Skin

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SP - 115

EP - 118

JO - Archives of Dermatological Research

JF - Archives of Dermatological Research

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ER -

Exploring the role of prolactin in psoriasis

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Keywords

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