Extended Metabolic Space Modeling

Pablo Carbonell, B Delepine, Jean-Loup Faulon

    Research output: Chapter in Book/Conference proceedingChapterpeer-review

    Abstract

    Determining the fraction of the chemical space that can be processed in vivo by using natural and synthetic biology devices is crucial for the development of advanced synthetic biology applications. The extended metabolic space is a coding system based on molecular signatures that enables the derivation of reaction rules for metabolic reactions and the enumeration of all possible substrates and products corresponding to the rules. The extended metabolic space expands capabilities for controlling the production, processing, sensing, and the release of specific molecules in chassis organisms.
    Original languageEnglish
    Title of host publicationSynthetic Metabolic Pathways
    PublisherSpringer Nature
    Pages83-96
    DOIs
    Publication statusPublished - 2017

    Publication series

    NameMethods in Molecular Biology

    Keywords

    • Metabolic modeling
    • Enzyme reactions
    • Metabolic pathways

    Research Beacons, Institutes and Platforms

    • Manchester Institute of Biotechnology

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