Abstract
We consider a simple Markov model for the spread of a disease caused by two virus strains in a closed homogeneously mixing population of size Ν. The spread of each strain in the absence of the other one is described by the stochastic SIS logistic epidemic process, and we assume that there is perfect cross-immunity between the two strains, that is, individuals infected by one are temporarily immune to re-infections and infections by the other. For the case where one strain is strictly stronger than the other, and the stronger strain on its own is supercritical, we derive precise asymptotic results for the distribution of the time when the weaker strain disappears from the population. We further extend our results to certain parameter values where the difference between the basic reproductive ratios of the two strains may tend to 0 as Ν → ∞.
Original language | English |
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Pages (from-to) | 2880-2922 |
Number of pages | 43 |
Journal | Annals of Applied Probability |
Volume | 30 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 2020 |
Keywords
- competing SIS epidemics
- near-critical epidemic
- Stochastic SIS logistic epidemic
- time to extinction