Extracellular Matrix Molecule-Based Capture of Mesenchymal Stromal Cells Under Flow

Teresa Massam-Wu, Stuart A Cain, Catherine Kielty

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


We present a method to capture mesenchymal stromal cells (MSCs) by adhesion to extracellular matrix (ECM) molecules under flow conditions. The technique simulates a physiological system and exploits the natural biological interactions of cells, through integrin receptors, with their ECM. The system offers an insight into how MSCs could be targeted/localized to the site of interest (graft) following intravenous injection.

Original languageEnglish
Title of host publicationThe Surfaceome
PublisherHumana Press, Inc
Number of pages12
ISBN (Electronic)978-1-4939-7553-2
ISBN (Print)978-1-4939-7551-8
Publication statusPublished - 2018

Publication series

NameMethods in molecular biology (Clifton, N.J.)
PublisherHumana Press, Inc.
ISSN (Print)1064-3745


  • Journal Article


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