Abstract
A microfluidic device with integrated spectrophotometric elements has been injection molded in poly(methyl methacrylate) (PMMA). The strategy for producing the device combined the direct photopatterning, replica molding techniques and a rapid cooled release mechanism in conjunction with material-material transfer to form a multilayer epoxy master on an injection mold insert. An injection-molded flow cell consisting of 1800 diffractive elements patterned on 25-μm-high PMMA pillars was produced. The design incorporated a large cross sectional surround, simplifying the alignment and bonding procedure. The absorbance range of one of the devices was standardized against a commercially available visible spectrophotometer at 605 nm to increasing concentrations of Nile blue perchlorate A dye in aqueous solution. The detection limit for a new integrated device was 1.2 × 10-6 m/Lof the mentioned dye.
| Original language | English |
|---|---|
| Pages (from-to) | 238-243 |
| Number of pages | 5 |
| Journal | Analytical Chemistry |
| Volume | 76 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Jan 2004 |
Keywords
- Spectrometers (cells
- fabrication of a spectrophotometric absorbance flow cell using injection-molded plastic)
- Spectrophotometry (fabrication of a spectrophotometric absorbance flow cell using injection-molded plastic)
- Molded plastics Role: ARU (Analytical role, unclassified), DEV (Device component use), ANST (Analytical study), USES (Uses) (fabrication of a spectrophotometric absorbance flow cell using injection-molded plastic)
- spectrophotometric absorbance flow cell injection molded plastic