Factors associated with kidney disease progression and mortality in a referred CKD population

Richard A. Hoefield, Philip A. Kalra, Patricia Baker, Beverley Lane, John P. New, Donal J. O'Donoghue, Robert N. Foley, Rachel J. Middleton

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background Knowing how kidney disease progresses is important for decision making in patients with chronic kidney disease (CKD) and for designing clinical services. Study Design Prospective cohort study. Setting & Participants We examined renal function trajectories in CRISIS (Chronic Renal Insufficiency Standards Implementation Study), in which 1,325 patients with CKD stages 3-5 and mean age of 65.1 years were followed up prospectively for a median of 26 months after referral to a regional nephrology center in the United Kingdom. By protocol, estimated glomerular filtration rate was determined every 12 months. Predictors CKD stage defined as estimated glomerular filtration rate
    Original languageEnglish
    Pages (from-to)1072-1081
    Number of pages9
    JournalAmerican Journal of Kidney Diseases
    Volume56
    Issue number6
    DOIs
    Publication statusPublished - Dec 2010

    Keywords

    • Chronic kidney disease (CKD)
    • Epidemiology
    • Estimated glomerular filtration rate (eGFR)
    • Mortality
    • Progression

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