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Factors influencing the differentiation of embryonal carcinoma and embryo-derived stem cells

  • J. Philippa Fisher
  • , Sarah A. Hope
  • , Martin L. Hooper

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The effects of aggregation, retinoic acid, and medium conditioned by Buffalo rat liver (BRL) cells, alone and in combination, on the differentiation of PSA4TG12 embryonal carcinoma and E14 embryonal stem cells are reported. The observations indicate that BRL-conditioned medium has more than one effect on the differentiation process, that retinoic acid has at least two effects which operate in different concentration ranges, and that both agents influence the choice of differentiation pathway as well as the extent of differentiation. © 1989.
    Original languageEnglish
    Pages (from-to)403-414
    Number of pages11
    JournalExperimental Cell Research
    Volume182
    Issue number2
    Publication statusPublished - Jun 1989

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

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