Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array

Fotis A. Kotasidis; Julian C. Matthews; Georgios I. Angelis; Philip J. Noonan; Pawel J. Markiewicz; William R. Lionheart; Andrew J. Reader

doi:10.1109/NSSMIC.2010.5874471

Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array

Fotis A. Kotasidis, Julian C. Matthews, Georgios I. Angelis, Philip J. Noonan, Pawel J. Markiewicz, William R. Lionheart, Andrew J. Reader

Research output: Chapter in Book/Conference proceeding › Conference contribution

Abstract

Incorporation of the resolution modelling component of the scanner during statistical image reconstruction often produces images of improved signal-to-noise ratio (SNR). In our previous work we measured and parameterized the Hi-Rez PET/CT scanner's point spread function (PSF) in image space using printed point source arrays at multiple positions. Here we extend the work to the TruePoint PET/CT and specifically report on i) optimizing the PSF model ii) demonstrating that a simple, single scan of a printed point source array is sufficient to accurately characterize the resolution blurring properties of the TruePoint PET/CT iii) evaluating and validating an image based resolution modelled reconstruction algorithm incorporating the measured scanner response against the scanner's projection based resolution modelled reconstruction algorithm on phantom data. A single array of 126 (149) point sources was scanned at different axial and azimuthal positions to measure the symmetric properties of the PSF model in image space. Results show that the blurring is more pronounced in the axial direction due to the spatial resolution losses incurred by the large span (span 11) used during binning of the raw data. As expected, the 3D resolution kernel varies in the axial, radial and tangential directions, but it is importantly shown that these variations can be captured and factorized into separate radial and axial dependencies. With this parameterization for the PSF, a single scan of the array can characterize the image-based PSF without compromising the accuracy of the measured model. This provides a fast, efficient and practical means of measuring the unique resolution modelling component of the system matrix on a scanner-by-scanner basis. For scanners also having the option of a PSF reconstruction, this fast and practical procedure can be used to rapidly check and if necessary correct any drift in the blurring properties of the scanner on a routine basis. © 2010 IEEE.

Original language	English
Title of host publication	IEEE Nuclear Science Symposium Conference Record\|IEEE Nucl. Sci. Symp. Conf. Rec.
Pages	3558-3562
Number of pages	4
DOIs	https://doi.org/10.1109/NSSMIC.2010.5874471
Publication status	Published - 2010
Event	2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010 - Knoxville, TN Duration: 1 Jul 2010 → …

Conference

Conference	2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010
City	Knoxville, TN
Period	1/07/10 → …

Keywords

image reconstruction
PET/CT
point spread function
printed point sources
PSF

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10.1109/NSSMIC.2010.5874471

Cite this

Kotasidis, F. A., Matthews, J. C., Angelis, G. I., Noonan, P. J., Markiewicz, P. J., Lionheart, W. R., & Reader, A. J. (2010). Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array. In IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec. (pp. 3558-3562) https://doi.org/10.1109/NSSMIC.2010.5874471

@inproceedings{4e71f55f8ac648c8b80886bfc6574be0,

title = "Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array",

abstract = "Incorporation of the resolution modelling component of the scanner during statistical image reconstruction often produces images of improved signal-to-noise ratio (SNR). In our previous work we measured and parameterized the Hi-Rez PET/CT scanner's point spread function (PSF) in image space using printed point source arrays at multiple positions. Here we extend the work to the TruePoint PET/CT and specifically report on i) optimizing the PSF model ii) demonstrating that a simple, single scan of a printed point source array is sufficient to accurately characterize the resolution blurring properties of the TruePoint PET/CT iii) evaluating and validating an image based resolution modelled reconstruction algorithm incorporating the measured scanner response against the scanner's projection based resolution modelled reconstruction algorithm on phantom data. A single array of 126 (149) point sources was scanned at different axial and azimuthal positions to measure the symmetric properties of the PSF model in image space. Results show that the blurring is more pronounced in the axial direction due to the spatial resolution losses incurred by the large span (span 11) used during binning of the raw data. As expected, the 3D resolution kernel varies in the axial, radial and tangential directions, but it is importantly shown that these variations can be captured and factorized into separate radial and axial dependencies. With this parameterization for the PSF, a single scan of the array can characterize the image-based PSF without compromising the accuracy of the measured model. This provides a fast, efficient and practical means of measuring the unique resolution modelling component of the system matrix on a scanner-by-scanner basis. For scanners also having the option of a PSF reconstruction, this fast and practical procedure can be used to rapidly check and if necessary correct any drift in the blurring properties of the scanner on a routine basis. {\textcopyright} 2010 IEEE.",

keywords = "image reconstruction, PET/CT, point spread function, printed point sources, PSF",

author = "Kotasidis, {Fotis A.} and Matthews, {Julian C.} and Angelis, {Georgios I.} and Noonan, {Philip J.} and Markiewicz, {Pawel J.} and Lionheart, {William R.} and Reader, {Andrew J.}",

year = "2010",

doi = "10.1109/NSSMIC.2010.5874471",

language = "English",

isbn = "9781424491063",

pages = "3558--3562",

booktitle = "IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.",

note = "2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010 ; Conference date: 01-07-2010",

}

Kotasidis, FA, Matthews, JC, Angelis, GI, Noonan, PJ, Markiewicz, PJ, Lionheart, WR & Reader, AJ 2010, Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array. in IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.. pp. 3558-3562, 2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010, Knoxville, TN, 1/07/10. https://doi.org/10.1109/NSSMIC.2010.5874471

Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array. / Kotasidis, Fotis A.; Matthews, Julian C.; Angelis, Georgios I. et al.
IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.. 2010. p. 3558-3562.

Research output: Chapter in Book/Conference proceeding › Conference contribution

TY - GEN

T1 - Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array

AU - Kotasidis, Fotis A.

AU - Matthews, Julian C.

AU - Angelis, Georgios I.

AU - Noonan, Philip J.

AU - Markiewicz, Pawel J.

AU - Lionheart, William R.

AU - Reader, Andrew J.

PY - 2010

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N2 - Incorporation of the resolution modelling component of the scanner during statistical image reconstruction often produces images of improved signal-to-noise ratio (SNR). In our previous work we measured and parameterized the Hi-Rez PET/CT scanner's point spread function (PSF) in image space using printed point source arrays at multiple positions. Here we extend the work to the TruePoint PET/CT and specifically report on i) optimizing the PSF model ii) demonstrating that a simple, single scan of a printed point source array is sufficient to accurately characterize the resolution blurring properties of the TruePoint PET/CT iii) evaluating and validating an image based resolution modelled reconstruction algorithm incorporating the measured scanner response against the scanner's projection based resolution modelled reconstruction algorithm on phantom data. A single array of 126 (149) point sources was scanned at different axial and azimuthal positions to measure the symmetric properties of the PSF model in image space. Results show that the blurring is more pronounced in the axial direction due to the spatial resolution losses incurred by the large span (span 11) used during binning of the raw data. As expected, the 3D resolution kernel varies in the axial, radial and tangential directions, but it is importantly shown that these variations can be captured and factorized into separate radial and axial dependencies. With this parameterization for the PSF, a single scan of the array can characterize the image-based PSF without compromising the accuracy of the measured model. This provides a fast, efficient and practical means of measuring the unique resolution modelling component of the system matrix on a scanner-by-scanner basis. For scanners also having the option of a PSF reconstruction, this fast and practical procedure can be used to rapidly check and if necessary correct any drift in the blurring properties of the scanner on a routine basis. © 2010 IEEE.

AB - Incorporation of the resolution modelling component of the scanner during statistical image reconstruction often produces images of improved signal-to-noise ratio (SNR). In our previous work we measured and parameterized the Hi-Rez PET/CT scanner's point spread function (PSF) in image space using printed point source arrays at multiple positions. Here we extend the work to the TruePoint PET/CT and specifically report on i) optimizing the PSF model ii) demonstrating that a simple, single scan of a printed point source array is sufficient to accurately characterize the resolution blurring properties of the TruePoint PET/CT iii) evaluating and validating an image based resolution modelled reconstruction algorithm incorporating the measured scanner response against the scanner's projection based resolution modelled reconstruction algorithm on phantom data. A single array of 126 (149) point sources was scanned at different axial and azimuthal positions to measure the symmetric properties of the PSF model in image space. Results show that the blurring is more pronounced in the axial direction due to the spatial resolution losses incurred by the large span (span 11) used during binning of the raw data. As expected, the 3D resolution kernel varies in the axial, radial and tangential directions, but it is importantly shown that these variations can be captured and factorized into separate radial and axial dependencies. With this parameterization for the PSF, a single scan of the array can characterize the image-based PSF without compromising the accuracy of the measured model. This provides a fast, efficient and practical means of measuring the unique resolution modelling component of the system matrix on a scanner-by-scanner basis. For scanners also having the option of a PSF reconstruction, this fast and practical procedure can be used to rapidly check and if necessary correct any drift in the blurring properties of the scanner on a routine basis. © 2010 IEEE.

KW - image reconstruction

KW - PET/CT

KW - point spread function

KW - printed point sources

KW - PSF

U2 - 10.1109/NSSMIC.2010.5874471

DO - 10.1109/NSSMIC.2010.5874471

M3 - Conference contribution

SN - 9781424491063

SP - 3558

EP - 3562

BT - IEEE Nuclear Science Symposium Conference Record|IEEE Nucl. Sci. Symp. Conf. Rec.

T2 - 2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010

Y2 - 1 July 2010

ER -

Fast single scan derivation of the PSF resolution model on the TruePoint PET/CT using a printed point source array

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