FEITER-a new EIT instrument for functional brain imaging

We report on human tests of the new EIT-based system fEITER (functional Electrical Impedance Tomography of Evoked Responses), targeted principally at functional brain imaging. It is designed and built to medical standard BS EN 60601-1:2006 and clinical trials have been approved by the MHRA in the UK. fEITER integrates an EIT sub-system with an evoked response sub-system capable of providing visual, auditory or other stimuli, and the timing of each stimulus is recorded within the EIT data to a resolution of 500 microseconds. The EIT sub-system operates at 100 frames per second using 20 polar/near-polar current patterns distributed among 32 scalp electrodes that are arranged in a 3-dimensional array on the subject. Presently, current injection is fixed in firmware at 1 mA pk-pk and 10 kHz. Performance testing on inanimate subjects has shown voltage measurement SNR better than 75 dB, at 100 frames per second. We describe the fEITER system and give example topographic results for a human subject under no-stimulus (i.e. reference) conditions and on application of auditory stimuli. The system's excellent noise properties and temporal resolution show clearly the influence of basic physiological phenomena on the EIT voltages. In response to stimulus presentation, the voltage data contain fast components (∼100 ms) and components that persist for many seconds. © 2010 IOP Publishing Ltd.