@article{80d15343bdbb41a0ab959f5622453cdb,
title = "Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2 Signaling in Severe Asthma",
keywords = "Administration, Inhalation, Adrenal Cortex Hormones/therapeutic use, adult, aged, Anti-Asthmatic Agents/therapeutic use, Asthma/diagnosis, Biomarkers/analysis, breath tests, case-control studies, cross-sectional studies, drug resistance, Eosinophils/metabolism, exhalation, female, humans, male, middle aged, Nitric Oxide/analysis, severity of illness index",
author = "\{MRC UK Refractory Asthma Stratification programme (RASP-UK)\} and Simon Couillard and Rahul Shrimanker and Rekha Chaudhuri and Mansur, \{Adel H\} and McGarvey, \{Lorcan P\} and Heaney, \{Liam G\} and Fowler, \{Stephen J\} and Peter Bradding and Pavord, \{Ian D\} and Hinks, \{Timothy S C\}",
note = "Funding Information: Supported by a nonrestricted research grant from Sanofi Genzyme for investigator-initiated type 2 innovation research; by the National Institute for Health Research (NIHR Leicester Biomedical Research Centre and NIHR Oxford Biomedical Research Centre); by the Medical Research Council (MRC Refractory Asthma Stratification Programme); and in part by the Wellcome Trust (211050/Z/18/Z) and Beit Fellowship (211050/Z/18/A). The views expressed are those of the authors and not necessarily those of the National Health Service, the NIHR, or the Department of Health. Funding Information: Supported by NIH grants R01HL144599 (R.P.D.) and R35HL144805 (S.E.E.).",
year = "2021",
month = sep,
day = "15",
doi = "10.1164/rccm.202104-1040LE",
language = "English",
volume = "204",
pages = "731--734",
journal = "American Journal of Respiratory and Critical Care Medicine ",
issn = "1073-449X",
publisher = "American Thoracic Society",
number = "6",
}
