FGF signalling: Diverse roles during early vertebrate embryogenesis

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    Abstract

    Fibroblast growth factor (FGF) signalling has been implicated during several phases of early embryogenesis, including the patterning of the embryonic axes, the induction and/or maintenance of several cell lineages and the coordination of morphogenetic movements. Here, we summarise our current understanding of the regulation and roles of FGF signalling during early vertebrate development.
    Original languageEnglish
    Pages (from-to)3731-3742
    Number of pages11
    JournalDevelopment
    Volume137
    Issue number22
    DOIs
    Publication statusPublished - 15 Nov 2010

    Keywords

    • Embryogenesis
    • Fibroblast growth factor
    • Mesoderm
    • Morphogenesis
    • Patterning
    • Stem cells

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