First data on structure-activity relations for the antitumor complexes [RuCl4(azole)2]

Erwin Reisner, V B Arion, Bernhard K Keppler, Armando J Pombeiro, V Yu Kukushkin

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The authors discuss relationships between geometric isomerism, solvolysis, and redox potential of Ru(III) complexes and their antitumor activities as prodrugs. [on SciFinder (R)]
    Original languageEnglish
    Pages (from-to)137-139
    JournalJournal of the Russian Chemical Society
    Volume48
    Issue number4
    Publication statusPublished - 2004

    Keywords

    • Structure-activity relationship (antitumor
    • first data on structure-activity relations for antitumor complexes [RuCl4(azole)2]-)
    • Antitumor agents
    • Molecular structure-property relationship
    • Redox potential
    • Solvolysis (first data on structure-activity relations for antitumor complexes [RuCl4(azole)2]-)
    • Diastereomers (geometric
    • Drug delivery systems (prodrugs
    • Ruthenium complex antitumor structure prodrug isomerism solvolysis redox potential

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