FMRI of the Face-Processing Network in the Ventral Temporal Lobe of Awake and Anesthetized Macaques

Nikos Logothetis, Shih Pi Ku, Andreas S. Tolias, Nikos K. Logothetis, Jozien Goense

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The primate brain features specialized areas devoted to processing of faces, which human imaging studies localized in the superior temporal sulcus (STS) and ventral temporal cortex. Studies in macaque monkeys, in contrast, revealed face selectivity predominantly in the STS. While this discrepancy could result from a true species difference, it may simply be the consequence of technical difficulties in obtaining high-quality MR images from the ventral temporal lobe. By using an optimized fMRI protocol we here report face-selective areas in ventral TE, the parahippocampal cortex, the entorhinal cortex, and the hippocampus of awake macaques, in addition to those already known in the STS. Notably, the face-selective activation of these memory-related areas was observed although the animals were passively viewing and it was preserved even under anesthesia. These results point to similarly extensive cortical networks for face processing in humans and monkeys and highlight potential homologs of the human fusiform face area. © 2011 Elsevier Inc.
    Original languageEnglish
    Pages (from-to)352-362
    Number of pages10
    JournalNeuron
    Volume70
    Issue number2
    DOIs
    Publication statusPublished - 28 Apr 2011

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