Abstract
Azoles are the mainstay of oral therapy for aspergillosis. Azole resistance in Aspergillus has been reported infrequently. The first resistant isolate in Manchester, UK, was detected in 1999. In a clinical collection of 519 A. fumigatus isolates, the frequency of itraconazole resistance was 5%, a significant increase since 2004 (p
Original language | English |
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Pages (from-to) | 1068-1076 |
Number of pages | 8 |
Journal | Emerging infectious diseases |
Volume | 15 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jul 2009 |
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Dive into the research topics of 'Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure'. Together they form a unique fingerprint.Impacts
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Defining global antifungal azole resistance in Aspergillus – enhancing diagnostics and driving drug discovery
Denning, D. (Participant), Warn, P. (Participant), Bromley, M. (Participant), Bowyer, P. (Participant) & Moore, C. (Participant)
Impact: Health and wellbeing, Policy, Economic
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Diagnostics and novel life-saving therapies for aspergillosis
Denning, D. (Participant), Anderson, M. J. (Participant), Moore, C. (Participant), Warn, P. (Participant), Bowyer, P. (Participant), Bromley, M. (Participant), Smith, N. (Participant), Howard, S. (Participant) & Niven, R. (Participant)
Impact: Health impacts