From DNA binding to transcriptional activation: Is the TALE complete?

Nicoletta Bobola

doi:10.1083/jcb.201706113

From DNA binding to transcriptional activation: Is the TALE complete?

Nicoletta Bobola

Faculty of Biology, Medicine and Health

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Abstract

How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017.J.Cell Biol.https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription.

Original language	English
Pages (from-to)	2603-2605
Number of pages	3
Journal	Journal of Cell Biology
Volume	216
Issue number	9
Early online date	11 Aug 2017
DOIs	https://doi.org/10.1083/jcb.201706113
Publication status	Published - 2017

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title = "From DNA binding to transcriptional activation: Is the TALE complete?",

abstract = "How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017.J.Cell Biol.https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription.",

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From DNA binding to transcriptional activation: Is the TALE complete?

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