Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 71-80 |
| Journal | Clinical and Experimental Rheumatology |
| Volume | 31 |
| Issue number | 2 Suppl 76 |
| Publication status | Published - 2013 |
Fingerprint
Dive into the research topics of 'Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry.'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver
}
In: Clinical and Experimental Rheumatology, Vol. 31, No. 2 Suppl 76, 2013, p. 71-80.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry.
AU - Hunsche, Elke
AU - Krieg, Thomas
AU - Schwierin, Barbara
AU - Rosenberg, Daniel
A2 - Raffier, B
A2 - Hirschi, M
A2 - Trautinger, F
A2 - Schmidt, P
A2 - Stetter, M
A2 - Hundstorfer, M
A2 - Reinhart, V
A2 - Monshi, B
A2 - Pirkhammer, D
A2 - Richter, L
A2 - Hamberger, N
A2 - Metz, S
A2 - Feldmann, R
A2 - Semmelweis, K
A2 - Lackner, K
A2 - Tomi, N
A2 - Kolle, H
A2 - Hafner, F
A2 - Brodmann, M
A2 - Kuen-Spiegel, M
A2 - Minmair, G
A2 - Heil, P M
A2 - Broil, H
A2 - Holzer, G
A2 - Illmer, X
A2 - Rintelen, B
A2 - Sautner, J
A2 - Takacs, M
A2 - Thun, M
A2 - Zemanova, I
A2 - Soukup, T
A2 - Smrzova, A
A2 - Bohmova, J
A2 - Prochazkova, L
A2 - Nemec, P
A2 - Fojtik, Z
A2 - Suchy, D
A2 - Becvar, R
A2 - Olsen, A B
A2 - Sondergaard, K H
A2 - Luosu jarvi, R
A2 - Vidqvist, K-L
A2 - Madaule, S
A2 - Beneton, N
A2 - Maillard, H
A2 - Charlanne, H
A2 - GranelBrocard, F
A2 - Hachulla, E
A2 - Hatron, P Y
A2 - Jourdain, N
A2 - Lambert, M
A2 - Launay, D
A2 - Morell, S
A2 - Woijtasik, G
A2 - Skowron, F
A2 - Zenone, T
A2 - Dadban, A
A2 - Lok, C
A2 - Ferrandiz, D
A2 - MagyBertrand, N
A2 - Moiton, M P
A2 - Taieb, A
A2 - Balquiere, S
A2 - Belin, E
A2 - Droitcourt, C
A2 - Julien, S
A2 - Prey, S
A2 - Boulon, C
A2 - Constans, J
A2 - Doutre, M S
A2 - Kostrzwewa, E
A2 - Richez, C
A2 - Greco, M
A2 - Misery, L
A2 - Sassolas, B
A2 - Collet, E
A2 - Berthier, S
A2 - Leguy-Seguin, V
A2 - Imbert, B
A2 - Carpentier, P
A2 - Blaise, S
A2 - Couraud, A
A2 - Doeffel-Hantz, V
A2 - Spars, A
A2 - Bezanahary, H
A2 - Boussely, N
A2 - Dumonteil, S
A2 - Fauchais, A L
A2 - Goudran, G
A2 - Loustaud-Ratti, V
A2 - Manea, P
A2 - Vidal, E
A2 - Coppere, B
A2 - DesmursClavel, H
A2 - Girard-Madoux, M H
A2 - Hot, A
A2 - Ninet, J
A2 - Granel, B
A2 - Cohen, J D
A2 - Keynote, A
A2 - Khau van Kien, A
A2 - Le Quellec, A
A2 - Riviere, S
A2 - Rullier, P
A2 - Bessis, D
A2 - Farcas, C
A2 - Bravetti, V
A2 - Moline, T
A2 - Wahl, D
A2 - Zuily, S
A2 - Granel-Brocard, F
A2 - Agard, C
A2 - Durant, C
A2 - Fuzibet, J G
A2 - Queyrel, V
A2 - Berezne, A
A2 - Guillevin, L
A2 - Mouthon, L
A2 - Cabane, J
A2 - Tiev, K
A2 - Toledano, C
A2 - Lazareth, I
A2 - Michon-Pasturel, U
A2 - Priollet, P
A2 - Reguiai, Z
A2 - CazaletsLacoste, C
A2 - Jego, P
A2 - Letremy, A
A2 - Perlat, A
A2 - Duval-Modeste, A B
A2 - Chatelus, E
A2 - Chiffot, H
A2 - Sibillia, J
A2 - Sordet, C
A2 - Adoue, D
A2 - Couret, B
A2 - Moulis, G
A2 - Pugnet, G
A2 - Sailler, L
A2 - Diot, E
A2 - Gaches, F
A2 - Farge, D
A2 - Keshtmand, H
A2 - Frances, C
A2 - von Elling, A
A2 - Bora, D
A2 - Ebel, J
A2 - Ahmadi-Simab, K
A2 - Klein, E
A2 - Hahn, K
A2 - Schulze, K
A2 - Rasche, C
A2 - Riemekasten, G
A2 - Lee, H H
A2 - Deuschle, K
A2 - Mattat, K
A2 - Becker, M
A2 - Worm, M
A2 - Mensing, C
A2 - Klings, D
A2 - Mensing, H
A2 - Messall, J
A2 - Zuper, R
A2 - Eilbacher, P
A2 - Saar, P
A2 - Kaufmann, P
A2 - Hallermann, C
A2 - Schmidt, K
A2 - Wahn, H
A2 - Schildt, K
A2 - Schuart, T
A2 - Kaczmarczyk, A
A2 - Kellner, C
A2 - von Oelhafen, J
A2 - Baron von Bildering, P
A2 - Kunze, S
A2 - Kleiner, H J
A2 - Alsheimer, B
A2 - Schuetz, N
A2 - Miirker-Hermann, E
A2 - Gottl, K-H
A2 - Weiss, E
A2 - Reischel, N
A2 - Kern, S
A2 - Goettl, K H
A2 - GoetheUniversitiitsklinikum, J-W
A2 - Himsel, A
A2 - Henkemeier, U
A2 - Schwarting, A
A2 - Hazenbiller, A
A2 - Nichelmann, V
A2 - Rumbaur, C
A2 - Boesenberg, I
A2 - Schmeiser, T
A2 - Mueller-Ladner, U
A2 - Unholzer, A
A2 - Starz, H
A2 - Welzel, J
A2 - Plaumann, K
A2 - Stoeckl, F
A2 - Sperling, S
A2 - Podda, M
A2 - Wagner, N
A2 - Rapprich, H
A2 - Niedermeier, A
A2 - Messer, G
A2 - Sardy, M
A2 - Bekou, V
A2 - Dill-MUller, D
A2 - Wlodarz, M
A2 - Belloni, B
A2 - Huettig, B
A2 - Ziai, M
A2 - Hein, R
A2 - Kneitz, C
A2 - Federow, I
A2 - Schneider, K
A2 - Semmler, M
A2 - Hapke, S
A2 - Metzler, C
A2 - Stein, T
A2 - Enderlein, M
A2 - Kayser, M
A2 - Werthmann, M
A2 - Guenther, C U
A2 - Neul, S
A2 - Hellmich, B
A2 - Loeffler, C
A2 - Pflugfelder, J
A2 - Karaenke, P
A2 - Mueglich, C
A2 - Tony, H P
A2 - Marina, P
A2 - Popp, M
A2 - Mittag, M
A2 - Baumann, C
A2 - Scheib, E G
A2 - Brand, H
A2 - Wilhelm, H U
A2 - Bohm, J
A2 - Dyballa, J
A2 - Boehm, J
A2 - Taggeselle, J
A2 - LUthke, K
A2 - Wuerzburg, I
A2 - Niefanger, K
A2 - Mayer, L
A2 - Drabek, J
A2 - Harmuth, W
A2 - Dietl, S
A2 - Moritz, D
A2 - Gause, A
A2 - Gaubitz, M
A2 - Hallecker, A
A2 - Krupp, E
A2 - Rumpel, H
A2 - Moosig, F
A2 - Frey, P
A2 - Kahl, S
A2 - Linke, M
A2 - Merk, B
A2 - Bloching, H H
A2 - Ochs, W
A2 - Kurthen, R
A2 - Eiden, E
A2 - Guertler, I
A2 - Aries, P M
A2 - Kirchberg, S
A2 - Jahnke, K
A2 - Mettler, S
A2 - Toeller, S
A2 - Zwenger, S
A2 - Langer, H E
A2 - Deininger, F
A2 - Hartmann, F
A2 - Neeck, G
A2 - Neek, G
A2 - Wernitzsch, H
A2 - Meier, L
A2 - Herr, U
A2 - Meier, U
A2 - Aaig, W
A2 - Bruckner, L
A2 - Sheikh, N
A2 - Wollenhaupt, J
A2 - Krog, B
A2 - Wollersdorfer, E
A2 - Hall, R
A2 - Diehm, C
A2 - Tiggers, C
A2 - Peters, J
A2 - Kirschke, J
A2 - Schroeder, J O
A2 - Zeuner, R
A2 - Uhlig, S
A2 - Barth, S
A2 - Huegel, R
A2 - Glaeser, R
A2 - Schaefer, C
A2 - Monshausen, M
A2 - Mengden, T
A2 - Funkert, A
A2 - Blank, N
A2 - Lupaschko, S
A2 - Voss, B
A2 - Megahed, M
A2 - Sadeghlar, F
A2 - Seidel, M
A2 - Wasmuth, J C
A2 - Kreuter, A
A2 - Vosswinkel, J
A2 - Pfoehler, C
A2 - Gerber, A
A2 - Haust, M
A2 - Hoff, N P
A2 - Mota, R
A2 - Akanay-Diesel, S
A2 - Homey, B
A2 - Katzemich, A
A2 - Erfurt-Berge, C
A2 - Sticherling, M
A2 - Beyer, C
A2 - Distler, J
A2 - Mitchell, A
A2 - Freundlieb, C
A2 - Rushentsova, U
A2 - Hermanns, G
A2 - Blaschke, S
A2 - Fiene, M
A2 - Wessel, C
A2 - Norgauer, J
A2 - Rabe, B
A2 - Schuster, J
A2 - Scholz, J
A2 - Kremer, K
A2 - Robakidze-Torbahn, M
A2 - Moinzadeh, P
A2 - Dohse, A
A2 - Muhlack, A
A2 - Schultz, L
A2 - Schult, S
A2 - Frambach, Y
A2 - Kruse, S
A2 - Kettenbach, A
A2 - Fell, I
A2 - Schweda, K
A2 - Steinbrink, K
A2 - Podobinska, M
A2 - Fieri beck, G
A2 - Schanz, S
A2 - Pfeiffer, C
A2 - Hassel, R
A2 - Herrgott, I
A2 - Sunderkoetter, C
A2 - Guenzel, J
A2 - Athanassiou, P
A2 - Dimitroulas, T
A2 - Settas, L
A2 - Kritikos, I
A2 - Tsifetaki, N
A2 - Garyfallos, A
A2 - Vasilopoulos, D
A2 - Boura, P
A2 - Kamali, S
A2 - Aslanidis, S
A2 - Vlachoyannopoulos, P
A2 - Galanopoulo, V
A2 - Sakkas, L
A2 - Koutroubas, A
A2 - Elezoglou, T
A2 - Galanopoulos, N
A2 - Grier, A
A2 - Murray, M
A2 - O'Rourke, M
A2 - Del Papa, N
A2 - Maglione, W
A2 - Zeni, S
A2 - Foti, R
A2 - Benenati, A
A2 - De Vita, S
A2 - Ferraccioli, G
A2 - Grassi, W
A2 - de Angeli, R
A2 - Pomponio, G
A2 - Mussi, A
A2 - Colonna, L
A2 - Airo, P
A2 - Zingarelli, S
A2 - Scorza, R
A2 - Serverino, A
A2 - Puppo, F
A2 - Negrini, S
A2 - Roma, I
A2 - Salsano, F
A2 - Triolo, G
A2 - Mazzuca, S
A2 - Carignola, R
A2 - Gatti, S
A2 - Lunardi, G
A2 - Riccieri, V
A2 - Salvarani, C
A2 - Bajocchi, G
A2 - Varcasia, G
A2 - Marasini, B
A2 - Belloll, L
A2 - Matucci-Cerinic, M
A2 - de Luca, R
A2 - Stisi, S
A2 - Bellissimo, S
A2 - Fusaro, E
A2 - Pellerito, R
A2 - Cozzi, F
A2 - Rizzo, M
A2 - Bartoluzzi, A
A2 - Trotta, F
A2 - Cantatore, F
A2 - Corrado, A
A2 - Ferri, C
A2 - Colaci, M
A2 - Malavolta, N
A2 - Mule, R
A2 - Galeazzi, M
A2 - Lapadula, G
A2 - Mathieu, A
A2 - Vacca, A
A2 - Giacomelli, R
A2 - Cipriani, P
A2 - Montecucco, C M
A2 - Codullo, V
A2 - Bucci, R
A2 - Battaglia, E
A2 - Valentini, G
A2 - Cuomo, G
A2 - Terlizzi, N
A2 - Serafino, L
A2 - Reumatologia, U O
A2 - Bombardieri, S
A2 - Della Rossa, A
A2 - Doveri, M
A2 - Perricone, R
A2 - de Mattia, M
A2 - Pallotta, S
A2 - Groenendael, J H L M
A2 - Seys, P
A2 - Goekoop, R J
A2 - Han, K H
A2 - Wlarvens, M
A2 - Bonte-Mineur, F
A2 - de Bois, M H W
A2 - de Beus, W M
A2 - van Zeben, D
A2 - Vonk, M
A2 - Knaapen, H K A
A2 - Smit, A
A2 - Bootsma, H
A2 - Ton, E
A2 - Voskuyl, A
A2 - Dutmer, E A J
A2 - Stalk, J N
A2 - Madland, T-M
A2 - Seip, M
A2 - Hoffmann Vold, A M
A2 - Bitter, H
A2 - Stocklund Thomsen, R
A2 - Resende, C
A2 - Ponte, C
A2 - Martinho, S
A2 - Silva, F
A2 - Ferreira, P
A2 - Grilo, A
A2 - Riso, N
A2 - Santos, C
A2 - Camara, I
A2 - Costa, J
A2 - Alves, J
A2 - Oliveira, S
A2 - Almeida, I
A2 - Silva, I
A2 - Cordeiro, A
A2 - Coelho, P
A2 - Lukac, J
A2 - Dolnicar, A S
A2 - Espinosa, G
A2 - Mejia, J C
A2 - Ramos, M
A2 - Plasin Rodriguez, M A
A2 - Mera, A
A2 - Blanco, J S
A2 - Diaz, J J
A2 - Losada, L
A2 - Perez, E
A2 - Maneiro, J R
A2 - Caamano, M
A2 - Fermindez, S
A2 - Insua, S A
A2 - Barbado, J
A2 - Fonseca, E M
A2 - Nufio, F J
A2 - Castellvi, I
A2 - Garcia de Ia Pena, P
A2 - Bellido, D
A2 - Paulino, M
A2 - Garcia, P V
A2 - Salas, V
A2 - Minguez, M D
A2 - Sanchez, M A
A2 - Urrego, C
A2 - Martin, I
A2 - Rueda, A
A2 - Calvo, J
A2 - Ripoll, M M
A2 - Torres, M C
A2 - Corteguera, M
A2 - Maceiras, F
A2 - Cruz, J
A2 - Mosquera, J A
A2 - Gomez, R
A2 - Area, B
A2 - Carrio, I
A2 - Rubio, M
A2 - Castellvi Barranco, I
A2 - Santos, P
A2 - Simeon, C P
A2 - Fonollosa, V
A2 - Egurbide, M V
A2 - Garcia de Vicuna, R
A2 - Vicente, E
A2 - Villaverde, V
A2 - Fernandez, C
A2 - Garcia, E
A2 - Uson, J
A2 - Miguelez, R
A2 - Callejas, J L
A2 - Ortego, N
A2 - Roman, J
A2 - Alegre-Sancho, J J
A2 - Robles, A
A2 - Rios, J J
A2 - Bonilla, M G
A2 - Sanchez Andrade, A
A2 - Vazquez, T R
A2 - Miranda, J A
A2 - Saez, L
A2 - Zea, A
A2 - De la Puente, C
A2 - Martinez, F G
A2 - Aguirre, M A
A2 - Collado, P
A2 - Cruz, A
A2 - Crespo, M
A2 - Sanchez-Roman, J
A2 - Castillo, M J
A2 - Garcia, A M
A2 - Muniz, G
A2 - Hedin, P J
A2 - Stahl, C
A2 - Bracin, T
A2 - Nordin, A
A2 - Albertsson, K
A2 - Rydvald, Y
A2 - Thorsson, C
A2 - Hermansson, E
A2 - Maurer, B
A2 - Verner, D
A2 - Schmidt Bosshard, R
A2 - Hall, F
A2 - Murphy, K
A2 - Lamb, J
A2 - Anderson, M
A2 - Moots, R
A2 - Buch, M
A2 - Bissell, L
A2 - Madhok, R
A2 - Hampson, R
A2 - D'Cruz, D
A2 - Choong, L M
A2 - Gordon, P
A2 - Dobson, J
A2 - Salerno, R
A2 - Nisar, M
A2 - Williams, C
A2 - Wilcox, L
A2 - Denton, C
A2 - Ochiel, R
A2 - Ngcozana, T
A2 - Parker, L
A2 - Vincent, R
A2 - McHugh, N
A2 - Cole, S
A2 - Brown, S
A2 - James, J
A2 - Herrick, A
A2 - Manning, J
A2 - Moore, T
A2 - Faizal, A
A2 - Skyes, H
A2 - Smythe, A
A2 - Hamilton, A
PY - 2013
Y1 - 2013
N2 - OBJECTIVES: Digital ulcers (DUs) are frequent manifestations of systemic scleroderma (SSc). This study assessed functional limitations due to DUs among patients enrolled in the Digital Ulcer Outcome (DUO) Registry, an international, multicentre, observational registry of SSc patients with DU disease. METHODS: Patients completed at enrolment a DU-specific functional assessment questionnaire with a 1-month recall period, measuring impairment in work and daily activities, and hours of help needed from others. Physician-reported clinical parameters were used to describe the population. For patients who completed at least part of the questionnaire, descriptive analyses were performed for overall results, and stratified by number of DUs at enrolment. RESULTS: This study included 2327 patients who completed at least part of the questionnaire. For patients with 0, 1-2, and ≥3 DUs at enrolment, mean overall work impairment during the prior month among employed/self-employed patients was 28%, 42%, and 48%, respectively. Across all included patients, ability to perform daily activities was impaired on average by 35%, 54%, and 63%, respectively. Patients required a mean of 2.0, 8.7, and 8.8 hours of paid help and 17.0, 35.9, and 63.7 hours of unpaid help, respectively, due to DUs in the prior month. Patients with DUs had more complications and medication use than patients with no DUs. CONCLUSIONS: With increasing number of DUs, SSc patients reported more impairment in work and daily activities and required more support from others.
AB - OBJECTIVES: Digital ulcers (DUs) are frequent manifestations of systemic scleroderma (SSc). This study assessed functional limitations due to DUs among patients enrolled in the Digital Ulcer Outcome (DUO) Registry, an international, multicentre, observational registry of SSc patients with DU disease. METHODS: Patients completed at enrolment a DU-specific functional assessment questionnaire with a 1-month recall period, measuring impairment in work and daily activities, and hours of help needed from others. Physician-reported clinical parameters were used to describe the population. For patients who completed at least part of the questionnaire, descriptive analyses were performed for overall results, and stratified by number of DUs at enrolment. RESULTS: This study included 2327 patients who completed at least part of the questionnaire. For patients with 0, 1-2, and ≥3 DUs at enrolment, mean overall work impairment during the prior month among employed/self-employed patients was 28%, 42%, and 48%, respectively. Across all included patients, ability to perform daily activities was impaired on average by 35%, 54%, and 63%, respectively. Patients required a mean of 2.0, 8.7, and 8.8 hours of paid help and 17.0, 35.9, and 63.7 hours of unpaid help, respectively, due to DUs in the prior month. Patients with DUs had more complications and medication use than patients with no DUs. CONCLUSIONS: With increasing number of DUs, SSc patients reported more impairment in work and daily activities and required more support from others.
M3 - Article
C2 - 23910613
SN - 1593-098X
VL - 31
SP - 71
EP - 80
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
IS - 2 Suppl 76
ER -