Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics

Cédric Klumpp; Kostas Kostarelos; Maurizio Prato; Alberto Bianco

doi:10.1016/j.bbamem.2005.10.008

Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics

Cédric Klumpp, Kostas Kostarelos, Maurizio Prato, Alberto Bianco

Research output: Contribution to journal › Article › peer-review

Abstract

Functionalized carbon nanotubes (f-CNT) are emerging as a new family of nanovectors for the delivery of different types of therapeutic molecules. The application of CNT in the field of carrier-mediated delivery has become possible after the recent discovery of their capacity to penetrate into the cells. CNT can be loaded with active molecules by forming stable covalent bonds or supramolecular assemblies based on noncovalent interactions. Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules. © 2005 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	404-412
Number of pages	8
Journal	Biochimica et Biophysica Acta - Biomembranes
Volume	1758
Issue number	3
DOIs	https://doi.org/10.1016/j.bbamem.2005.10.008
Publication status	Published - Mar 2006

Keywords

Carbon nanotube
Drug delivery
Gene
Peptide
Vaccine
Vector

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10.1016/j.bbamem.2005.10.008

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title = "Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics",

abstract = "Functionalized carbon nanotubes (f-CNT) are emerging as a new family of nanovectors for the delivery of different types of therapeutic molecules. The application of CNT in the field of carrier-mediated delivery has become possible after the recent discovery of their capacity to penetrate into the cells. CNT can be loaded with active molecules by forming stable covalent bonds or supramolecular assemblies based on noncovalent interactions. Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules. {\textcopyright} 2005 Elsevier B.V. All rights reserved.",

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author = "C{\'e}dric Klumpp and Kostas Kostarelos and Maurizio Prato and Alberto Bianco",

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AU - Kostarelos, Kostas

AU - Prato, Maurizio

AU - Bianco, Alberto

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AB - Functionalized carbon nanotubes (f-CNT) are emerging as a new family of nanovectors for the delivery of different types of therapeutic molecules. The application of CNT in the field of carrier-mediated delivery has become possible after the recent discovery of their capacity to penetrate into the cells. CNT can be loaded with active molecules by forming stable covalent bonds or supramolecular assemblies based on noncovalent interactions. Once the cargos are carried into various cells, tissues and organs they are able to express their biological function. In this review, we will describe the potential of f-CNT to deliver different types of therapeutic molecules. © 2005 Elsevier B.V. All rights reserved.

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KW - Gene

KW - Peptide

KW - Vaccine

KW - Vector

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Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics

Abstract

Keywords

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