Future Therapeutic Directions for the Treatment of Psoriasis

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    The future management of psoriasis will depend on a number of distinct but ultimately inter-related strands of evidence, these are: (i) the interplay of genes and environment and the characterisation of psoriasis phenotypes; (ii) the role of pharmacogenetics in personalised healthcare; (iii) the translation of basic scientific discovery of relevant immune and angiogenic pathways into targeted biologic and small molecule therapies; and (iv) the recognition that the management of any chronic disease is enhanced by an understanding of psychosocial issues. A reductionist approach to development of new therapies will be paramount but serendipity and the prepared mind will contribute, as they have always done. © 2009 Academia Española de Dermatología y Venereología.
    Original languageEnglish
    Pages (from-to)28-31
    Number of pages3
    JournalActas Dermo-Sifiliograficas
    Issue number2
    Publication statusPublished - Dec 2009


    • biologic therapy
    • biologics
    • personalised medicine
    • pharmacogenetics
    • phenotypes
    • psoriasis


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