Future Therapeutic Directions for the Treatment of Psoriasis

R. B. Warren; C. E M Griffiths

doi:10.1016/S0001-7310(09)73375-7

Future Therapeutic Directions for the Treatment of Psoriasis

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Abstract

The future management of psoriasis will depend on a number of distinct but ultimately inter-related strands of evidence, these are: (i) the interplay of genes and environment and the characterisation of psoriasis phenotypes; (ii) the role of pharmacogenetics in personalised healthcare; (iii) the translation of basic scientific discovery of relevant immune and angiogenic pathways into targeted biologic and small molecule therapies; and (iv) the recognition that the management of any chronic disease is enhanced by an understanding of psychosocial issues. A reductionist approach to development of new therapies will be paramount but serendipity and the prepared mind will contribute, as they have always done. © 2009 Academia Española de Dermatología y Venereología.

Original language	English
Pages (from-to)	28-31
Number of pages	3
Journal	Actas Dermo-Sifiliograficas
Volume	100
Issue number	2
DOIs	https://doi.org/10.1016/S0001-7310(09)73375-7
Publication status	Published - Dec 2009

Keywords

biologic therapy
biologics
personalised medicine
pharmacogenetics
phenotypes
psoriasis

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10.1016/S0001-7310(09)73375-7

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abstract = "The future management of psoriasis will depend on a number of distinct but ultimately inter-related strands of evidence, these are: (i) the interplay of genes and environment and the characterisation of psoriasis phenotypes; (ii) the role of pharmacogenetics in personalised healthcare; (iii) the translation of basic scientific discovery of relevant immune and angiogenic pathways into targeted biologic and small molecule therapies; and (iv) the recognition that the management of any chronic disease is enhanced by an understanding of psychosocial issues. A reductionist approach to development of new therapies will be paramount but serendipity and the prepared mind will contribute, as they have always done. {\textcopyright} 2009 Academia Espa{\~n}ola de Dermatolog{\'i}a y Venereolog{\'i}a.",

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AU - Griffiths, C. E M

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KW - biologic therapy

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KW - personalised medicine

KW - pharmacogenetics

KW - phenotypes

KW - psoriasis

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Future Therapeutic Directions for the Treatment of Psoriasis

Abstract

Keywords

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