Gabapentin as a potential treatment for cough syncope

C.H. Wu; K. Gunasekara; J.H. Hull; A. Bikov; A.J. Morris; O.S. Usmani

doi:10.4187/respcare.03255

Gabapentin as a potential treatment for cough syncope

C.H. Wu, K. Gunasekara, J.H. Hull, A. Bikov, A.J. Morris, O.S. Usmani

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	e34-e37
Journal	Respiratory Care
Volume	60
Issue number	2
DOIs	https://doi.org/10.4187/respcare.03255
Publication status	Published - 2015

Keywords

beclometasone dipropionate plus formoterol fumarate
chlorpheniramine
codeine phosphate
gabapentin
lansoprazole
prednisolone
4 aminobutyric acid
amine
antitussive agent
cyclohexanecarboxylic acid derivative
adult
Article
case report
cough syncope
coughing
drug megadose
faintness
human
hypertension
male
middle aged
quality of life
social stress
treatment response
chronic disease
complication
Cough
Syncope
Amines
Antitussive Agents
Chronic Disease
Cyclohexanecarboxylic Acids
gamma-Aminobutyric Acid
Humans
Male
Middle Aged

Access to Document

10.4187/respcare.03255

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982717628&doi=10.4187%2frespcare.03255&partnerID=40&md5=858a3ce8b596ea7dba5de625eae247cd

Cite this

@article{5e17ca655e9f49dc93accc49a73f3bc4,

title = "Gabapentin as a potential treatment for cough syncope",

keywords = "beclometasone dipropionate plus formoterol fumarate, chlorpheniramine, codeine phosphate, gabapentin, lansoprazole, prednisolone, 4 aminobutyric acid, amine, antitussive agent, cyclohexanecarboxylic acid derivative, adult, Article, case report, cough syncope, coughing, drug megadose, faintness, human, hypertension, male, middle aged, quality of life, social stress, treatment response, chronic disease, complication, Cough, Syncope, Amines, Antitussive Agents, Chronic Disease, Cyclohexanecarboxylic Acids, gamma-Aminobutyric Acid, Humans, Male, Middle Aged",

author = "C.H. Wu and K. Gunasekara and J.H. Hull and A. Bikov and A.J. Morris and O.S. Usmani",

note = "Cited By :3 Export Date: 31 October 2018 CODEN: RECAC Correspondence Address: Wu, C.H.; Imperial College London, South Kensington CampusUnited Kingdom; email: [email protected] Chemicals/CAS: chlorpheniramine, 132-22-9; codeine phosphate, 52-28-8; gabapentin, 60142-96-3; lansoprazole, 103577-45-3; prednisolone, 50-24-8; 4 aminobutyric acid, 28805-76-7, 56-12-2; Amines; Antitussive Agents; Cyclohexanecarboxylic Acids; gabapentin; gamma-Aminobutyric Acid Funding details: MC_PC_13033, MRC, Medical Research Council References: Chung, K.F., Pavord, I.D., Prevalence, pathogenesis, and causes of chronic cough (2008) Lancet, 371 (9621), pp. 1364-1374; Dicpinigaitis, P.V., Morice, A.H., Birring, S.S., McGarvey, L., Smith, J.A., Canning, B.J., Page, C.P., Antitussive drugs–past, present, and future (2014) Pharmacol Rev, 66 (2), pp. 468-512; Chung, K.F., McGarvey, L., Mazzone, S.B., Chronic cough as a neuropathic disorder (2013) Lancet Respir Med, 1 (5), pp. 414-422; Ryan, N.M., Birring, S.S., Gibson, P.G., Gabapentin for refractory chronic cough: A randomised, double-blind, placebo-controlled trial (2012) Lancet, 380 (9853), pp. 1583-1589; Widdicombe, J.G., Afferent receptors in the airways and cough (1998) Respir Physiol, 114 (1), pp. 5-15; Shannon, R., Baekey, D.M., Morris, K.F., Lindsey, B.G., Ventrolateral medullary respiratory network and a model of cough motor pattern generation (1998) J Appl Physiol, 84 (6), pp. 2020-2035; Canning, B.J., Mori, N., Mazzone, S.B., Vagal afferent nerves regulating the cough reflex (2006) Respir Physiol Neurobiol, 152 (3), pp. 223-242; Schelegle, E.S., Green, J.F., An overview of the anatomy and physiology of slowly adapting pulmonary stretch receptors (2001) Respir Physiol, 125 (1-2), pp. 17-31; Kou, Y.R., Lee, L.Y., Stimulation of rapidly adapting receptors in canine lungs by a single breath of cigarette smoke (1990) J Appl Physiol, 68 (3), pp. 1203-1210; Undem, B.J., Carr, M.J., Kollarik, M., Physiology and plasticity of putative cough fibres in the guinea pig (2002) Pulm Pharmacol Ther, 15 (3), pp. 193-198; Undem, B.J., Chuaychoo, B., Lee, M.G., Weinreich, D., Myers, A.C., Kollarik, M., Subtypes of vagal afferent C-fibres in guinea-pig lungs (2004) J Physiol, 556, pp. 905-917; Caterina, M.J., Julius, D., The vanilloid receptor: A molecular gateway to the pain pathway (2001) Annu Rev Neurosci, 24, pp. 487-517; Groneberg, D.A., Niimi, A., Dinh, Q.T., Cosio, B., Hew, M., Fischer, A., Chung, K.F., Increased expression of transient receptor potential vanilloid- 1 in airway nerves of chronic cough (2004) Am J Respir Crit Care Med, 170 (12), pp. 1276-1280; Choudry, N.B., Fuller, R.W., Sensitivity of the cough reflex in patients with chronic cough (1992) Eur Respir J, 5 (3), pp. 296-300; Spina, D., Page, C.P., Regulating cough through modulation of sensory nerve function in the airways (2013) Pulm Pharmacol Ther, 26 (5), pp. 486-490; Schappert, S.M., National Ambulatory Medical Care Survey: 1991 summary (1994) Vital Health Stat, 13 (116), pp. 1-110; Mattle, H.P., Nirkko, A.C., Baumgartner, R.W., Sturzenegger, M., Transient cerebral circulatory arrest coincides with fainting in cough syncope (1995) Neurology, 45 (3), pp. 498-501; Maznyczka, A., Squire, I.B., Cough syncope–a diagnosis under pressure (2010) Lancet, 376 (9739), 486p; Bolser, D.C., Davenport, P.W., Codeine and cough: An ineffective gold standard (2007) Curr Opin Allergy Clin Immunol, 7 (1), pp. 32-36; Chang, C.C., Cheng, A.C., Chang, A.B., Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults (2007) Cochrane Database Syst Rev, (4). , CD006088; Bolser, D.C., Aziz, S.M., Degennaro, F.C., Kreutner, W., Egan, R.W., Siegel, M.I., Chapman, R.W., Antitussive effects of GABAB agonists in the cat and guinea-pig (1993) Br J Pharmacol, 110 (1), pp. 491-495; Mutolo, D., Bongianni, F., Cinelli, E., Pantaleo, T., Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit (2010) J Appl Physiol, 109 (4), pp. 1002-1010; Faruqi, S., Molyneux, I.D., Fathi, H., Wright, C., Thompson, R., Morice, A.H., Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study (2011) Respirology, 16 (7), pp. 1150-1156; Cheng, J.K., Chiou, L.C., Mechanisms of the antinociceptive action of gabapentin (2006) J Pharmacol Sci, 100 (5), pp. 471-486; Chapman, R.W., Hey, J.A., Rizzo, C.A., Bolser, D.C., GABAB receptors in the lung (1993) Trends Pharmacol Sci, 14 (1), pp. 26-29; Ford, P.A., Barnes, P.J., Usmani, O.S., Chronic cough and Holmes-Adie syndrome (2007) Lancet, 369 (9558), 342p; Lee, B., Woo, P., Chronic cough as a sign of laryngeal sensory neuropathy: Diagnosis and treatment (2005) Ann Otol Rhinol Laryngol, 114 (4), pp. 253-257; Mintz, S., Lee, J.K., Gabapentin in the treatment of intractable idiopathic chronic cough: Case reports (2006) Am J Med, 119 (5), pp. e13-e15; Van De Kerkhove, C., Goeminne, P.C., Van Bleyenbergh, P., Dupont, L.J., A cohort description and analysis of the effect of gabapentin on idiopathic cough (2012) Cough, 8, 9p",

year = "2015",

doi = "10.4187/respcare.03255",

language = "English",

volume = "60",

pages = "e34--e37",

journal = "Respiratory Care",

issn = "0020-1324",

publisher = "American Association for Respiratory Care",

number = "2",

}

TY - JOUR

T1 - Gabapentin as a potential treatment for cough syncope

AU - Wu, C.H.

AU - Gunasekara, K.

AU - Hull, J.H.

AU - Bikov, A.

AU - Morris, A.J.

AU - Usmani, O.S.

N1 - Cited By :3 Export Date: 31 October 2018 CODEN: RECAC Correspondence Address: Wu, C.H.; Imperial College London, South Kensington CampusUnited Kingdom; email: [email protected] Chemicals/CAS: chlorpheniramine, 132-22-9; codeine phosphate, 52-28-8; gabapentin, 60142-96-3; lansoprazole, 103577-45-3; prednisolone, 50-24-8; 4 aminobutyric acid, 28805-76-7, 56-12-2; Amines; Antitussive Agents; Cyclohexanecarboxylic Acids; gabapentin; gamma-Aminobutyric Acid Funding details: MC_PC_13033, MRC, Medical Research Council References: Chung, K.F., Pavord, I.D., Prevalence, pathogenesis, and causes of chronic cough (2008) Lancet, 371 (9621), pp. 1364-1374; Dicpinigaitis, P.V., Morice, A.H., Birring, S.S., McGarvey, L., Smith, J.A., Canning, B.J., Page, C.P., Antitussive drugs–past, present, and future (2014) Pharmacol Rev, 66 (2), pp. 468-512; Chung, K.F., McGarvey, L., Mazzone, S.B., Chronic cough as a neuropathic disorder (2013) Lancet Respir Med, 1 (5), pp. 414-422; Ryan, N.M., Birring, S.S., Gibson, P.G., Gabapentin for refractory chronic cough: A randomised, double-blind, placebo-controlled trial (2012) Lancet, 380 (9853), pp. 1583-1589; Widdicombe, J.G., Afferent receptors in the airways and cough (1998) Respir Physiol, 114 (1), pp. 5-15; Shannon, R., Baekey, D.M., Morris, K.F., Lindsey, B.G., Ventrolateral medullary respiratory network and a model of cough motor pattern generation (1998) J Appl Physiol, 84 (6), pp. 2020-2035; Canning, B.J., Mori, N., Mazzone, S.B., Vagal afferent nerves regulating the cough reflex (2006) Respir Physiol Neurobiol, 152 (3), pp. 223-242; Schelegle, E.S., Green, J.F., An overview of the anatomy and physiology of slowly adapting pulmonary stretch receptors (2001) Respir Physiol, 125 (1-2), pp. 17-31; Kou, Y.R., Lee, L.Y., Stimulation of rapidly adapting receptors in canine lungs by a single breath of cigarette smoke (1990) J Appl Physiol, 68 (3), pp. 1203-1210; Undem, B.J., Carr, M.J., Kollarik, M., Physiology and plasticity of putative cough fibres in the guinea pig (2002) Pulm Pharmacol Ther, 15 (3), pp. 193-198; Undem, B.J., Chuaychoo, B., Lee, M.G., Weinreich, D., Myers, A.C., Kollarik, M., Subtypes of vagal afferent C-fibres in guinea-pig lungs (2004) J Physiol, 556, pp. 905-917; Caterina, M.J., Julius, D., The vanilloid receptor: A molecular gateway to the pain pathway (2001) Annu Rev Neurosci, 24, pp. 487-517; Groneberg, D.A., Niimi, A., Dinh, Q.T., Cosio, B., Hew, M., Fischer, A., Chung, K.F., Increased expression of transient receptor potential vanilloid- 1 in airway nerves of chronic cough (2004) Am J Respir Crit Care Med, 170 (12), pp. 1276-1280; Choudry, N.B., Fuller, R.W., Sensitivity of the cough reflex in patients with chronic cough (1992) Eur Respir J, 5 (3), pp. 296-300; Spina, D., Page, C.P., Regulating cough through modulation of sensory nerve function in the airways (2013) Pulm Pharmacol Ther, 26 (5), pp. 486-490; Schappert, S.M., National Ambulatory Medical Care Survey: 1991 summary (1994) Vital Health Stat, 13 (116), pp. 1-110; Mattle, H.P., Nirkko, A.C., Baumgartner, R.W., Sturzenegger, M., Transient cerebral circulatory arrest coincides with fainting in cough syncope (1995) Neurology, 45 (3), pp. 498-501; Maznyczka, A., Squire, I.B., Cough syncope–a diagnosis under pressure (2010) Lancet, 376 (9739), 486p; Bolser, D.C., Davenport, P.W., Codeine and cough: An ineffective gold standard (2007) Curr Opin Allergy Clin Immunol, 7 (1), pp. 32-36; Chang, C.C., Cheng, A.C., Chang, A.B., Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults (2007) Cochrane Database Syst Rev, (4). , CD006088; Bolser, D.C., Aziz, S.M., Degennaro, F.C., Kreutner, W., Egan, R.W., Siegel, M.I., Chapman, R.W., Antitussive effects of GABAB agonists in the cat and guinea-pig (1993) Br J Pharmacol, 110 (1), pp. 491-495; Mutolo, D., Bongianni, F., Cinelli, E., Pantaleo, T., Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit (2010) J Appl Physiol, 109 (4), pp. 1002-1010; Faruqi, S., Molyneux, I.D., Fathi, H., Wright, C., Thompson, R., Morice, A.H., Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study (2011) Respirology, 16 (7), pp. 1150-1156; Cheng, J.K., Chiou, L.C., Mechanisms of the antinociceptive action of gabapentin (2006) J Pharmacol Sci, 100 (5), pp. 471-486; Chapman, R.W., Hey, J.A., Rizzo, C.A., Bolser, D.C., GABAB receptors in the lung (1993) Trends Pharmacol Sci, 14 (1), pp. 26-29; Ford, P.A., Barnes, P.J., Usmani, O.S., Chronic cough and Holmes-Adie syndrome (2007) Lancet, 369 (9558), 342p; Lee, B., Woo, P., Chronic cough as a sign of laryngeal sensory neuropathy: Diagnosis and treatment (2005) Ann Otol Rhinol Laryngol, 114 (4), pp. 253-257; Mintz, S., Lee, J.K., Gabapentin in the treatment of intractable idiopathic chronic cough: Case reports (2006) Am J Med, 119 (5), pp. e13-e15; Van De Kerkhove, C., Goeminne, P.C., Van Bleyenbergh, P., Dupont, L.J., A cohort description and analysis of the effect of gabapentin on idiopathic cough (2012) Cough, 8, 9p

PY - 2015

Y1 - 2015

KW - beclometasone dipropionate plus formoterol fumarate

KW - chlorpheniramine

KW - codeine phosphate

KW - gabapentin

KW - lansoprazole

KW - prednisolone

KW - 4 aminobutyric acid

KW - amine

KW - antitussive agent

KW - cyclohexanecarboxylic acid derivative

KW - adult

KW - Article

KW - case report

KW - cough syncope

KW - coughing

KW - drug megadose

KW - faintness

KW - human

KW - hypertension

KW - male

KW - middle aged

KW - quality of life

KW - social stress

KW - treatment response

KW - chronic disease

KW - complication

KW - Cough

KW - Syncope

KW - Amines

KW - Antitussive Agents

KW - Chronic Disease

KW - Cyclohexanecarboxylic Acids

KW - gamma-Aminobutyric Acid

KW - Humans

KW - Male

KW - Middle Aged

U2 - 10.4187/respcare.03255

DO - 10.4187/respcare.03255

M3 - Article

SN - 0020-1324

VL - 60

SP - e34-e37

JO - Respiratory Care

JF - Respiratory Care

IS - 2

ER -