Gene cloning to clinical trials-the trials and tribulations of a life with collagen

Ray P Boot-Handford

doi:10.1111/iep.12311

Gene cloning to clinical trials-the trials and tribulations of a life with collagen

Ray P Boot-Handford

Division of Cell Matrix Biology & Regenerative Medicine (L5)

Research output: Contribution to journal › Review article › peer-review

Abstract

This review, based on the BSMB Fell‐Muir Lecture I presented in July 2018 at the Matrix Biology Europe Conference in Manchester, gives a personal perspective of my own laboratory's contributions to research into type X collagen, metaphyseal chondrodysplasia type Schmid and potential treatments for this disorder that are currently entering clinical trial. I have tried to set the advances made in the context of the scientific technologies available at the time and how these have changed over the more than three decades of this research.

Original language	English
Pages (from-to)	4-11
Number of pages	8
Journal	International Journal of Experimental Pathology
Volume	100
Issue number	1
Early online date	26 Mar 2019
DOIs	https://doi.org/10.1111/iep.12311
Publication status	Published - 16 Apr 2019

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10.1111/iep.12311

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Gene cloning to clinical trials-the trials and tribulations of a life with collagen

Abstract

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