Generation of anisotropic-smoothness regularization filters for EIT.

Andrea Borsic, William R B Lionheart, Christopher N McLeod

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In the inverse conductivity problem, as in any ill-posed inverse problem, regularization techniques are necessary in order to stabilize inversion. A common way to implement regularization in electrical impedance tomography is to use Tikhonov regularization. The inverse problem is formulated as a minimization of two terms: the mismatch of the measurements against the model, and the regularization functional. Most commonly, differential operators are used as regularization functionals, leading to smooth solutions. Whenever the imaged region presents discontinuities in the conductivity distribution, such as interorgan boundaries, the smoothness prior is not consistent with the actual situation. In these cases, the reconstruction is enhanced by relaxing the smoothness constraints in the direction normal to the discontinuity. In this paper, we derive a method for generating Gaussian anisotropic regularization filters. The filters are generated on the basis of the prior structural information, allowing a better reconstruction of conductivity profiles matching these priors. When incorporating prior information into a reconstruction algorithm, the risk is of biasing the inverse solutions toward the assumed distributions. Simulations show that, with a careful selection of the regularization parameters, the reconstruction algorithm is still able to detect conductivities patterns that violate the prior information. A generalized singular-value decomposition analysis of the effects of the anisotropic filters on regularization is presented in the last sections of the paper.
    Original languageEnglish
    Pages (from-to)579-587
    Number of pages8
    JournalIEEE Transactions on Medical Imaging
    Volume21
    Issue number6
    DOIs
    Publication statusPublished - Jun 2002

    Keywords

    • Anisotropic smoothing
    • Electrical impedance tomography
    • GSVD
    • Prior information
    • Regularization

    Fingerprint

    Dive into the research topics of 'Generation of anisotropic-smoothness regularization filters for EIT.'. Together they form a unique fingerprint.

    Cite this