Abstract
In a previous study, we analyzed meiotic recombination events that occurred in the 22-kb region (LEU2 to CEN3) of chromosome III of Sacchromyces cerevisiae. We found one region with an enhanced level of crossovers (a hotspot) and one region with a depressed level of crossovers. In this study, we show that about one-third of the crossovers that occur between LEU2 and CEN3 are initiated in a 1.3-kb region located approximately 6 kb from the centromere. Both crossovers and gene conversion events are initiated at this site. Events initiated at this position can be resolved as crossovers in regions located either centromere-distally or centromere-proximally from the initiation site.
| Original language | English |
|---|---|
| Pages (from-to) | 717-727 |
| Number of pages | 10 |
| Journal | Genetics |
| Volume | 128 |
| Issue number | 4 |
| Publication status | Published - 1991 |
Research Beacons, Institutes and Platforms
- Manchester Institute of Biotechnology