Genetic control of chromosome length in yeast

  • R. M. Walmsley
  • , T. D. Petes

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The chromosomes of the yeast Saccharomyces cerevisiae terminate with sequences that have the form poly(C1-3-A). In this paper, we show that within an individual yeast strain all chromosomes end with tracts of poly(C1-3-A) of similar lengths; however, different strains can have tracts that vary in length by a factor of two. By a genetic analysis, we demonstrate that yeast cells have a mechanism that allows them to change rapidly the length of their chromosomes by altering the length of the poly(C1-3-A) tract.
    Original languageEnglish
    Pages (from-to)506-510
    Number of pages4
    JournalProceedings of the National Academy of Sciences of the United States of America
    Volume82
    Issue number2
    Publication statusPublished - 1985

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