TY - JOUR
T1 - Geometric distortion caused by metallic femoral head prosthesis in prostate cancer imaging on an MR linac
T2 - in-vivo measurements of spatial deformation
AU - Mcdaid, Lisa
AU - Clough, A
AU - Benson, KR
AU - Nelder, C
AU - Mcmahon, J
AU - Jackson, S
AU - Aznar, M
AU - Choudhury, AC
AU - van Herk, M
AU - Eccles, CL
PY - 2024/4/1
Y1 - 2024/4/1
N2 - OBJECTIVES: Metallic implants cause artefacts and distortion on MRI. To ensure accurate dose delivery and plan adaptation on an MR Linac, there is a need to evaluate distortion caused.METHODS: Participants were imaged on an MR Linac (Elekta Unity, Elekta AB Stockholm). Three sequences were evaluated. Two vendor supplied (T2W TSE 3D), and one T2W TSE 3D optimized to reduce metal artefact distortions. Images were rigidly registered to CT images by a single observer, using bony anatomy. Three coronal and three axial images were selected, and six paired, adjacent, bony landmarks were identified on each slice. Images bisecting treatment isocentre were included. Difference between landmark coordinates was taken to be measure of distortion.RESULTS: Five observers participated. Thirty six pairs of bony landmarks were identified. Median difference in position of landmarks was ≤3 mm (range 0.3-4.4 mm). One-way analysis of variance (ANOVA) between observer means showed no significant variation between sequences or patients (P = 1.26 in plane, P = 0.11 through plane). Interobserver intra class correlation (ICC) was 0.70 in-plane and 0.78 through-plane. Intra-observer ICC for three observers was 0.76, 0.81, 0.83, showing moderate to good reliability on this small cohort.CONCLUSIONS: This in-vivo feasibility study suggests distortion due to metallic hip prosthesis is not an obstacle for pelvic radiotherapy on an MR Linac. Research on the impact on plan quality is warranted.ADVANCES IN KNOWLEDGE: This work supports feasibility of treating patients with metallic hip prosthesis on an MR Linac.
AB - OBJECTIVES: Metallic implants cause artefacts and distortion on MRI. To ensure accurate dose delivery and plan adaptation on an MR Linac, there is a need to evaluate distortion caused.METHODS: Participants were imaged on an MR Linac (Elekta Unity, Elekta AB Stockholm). Three sequences were evaluated. Two vendor supplied (T2W TSE 3D), and one T2W TSE 3D optimized to reduce metal artefact distortions. Images were rigidly registered to CT images by a single observer, using bony anatomy. Three coronal and three axial images were selected, and six paired, adjacent, bony landmarks were identified on each slice. Images bisecting treatment isocentre were included. Difference between landmark coordinates was taken to be measure of distortion.RESULTS: Five observers participated. Thirty six pairs of bony landmarks were identified. Median difference in position of landmarks was ≤3 mm (range 0.3-4.4 mm). One-way analysis of variance (ANOVA) between observer means showed no significant variation between sequences or patients (P = 1.26 in plane, P = 0.11 through plane). Interobserver intra class correlation (ICC) was 0.70 in-plane and 0.78 through-plane. Intra-observer ICC for three observers was 0.76, 0.81, 0.83, showing moderate to good reliability on this small cohort.CONCLUSIONS: This in-vivo feasibility study suggests distortion due to metallic hip prosthesis is not an obstacle for pelvic radiotherapy on an MR Linac. Research on the impact on plan quality is warranted.ADVANCES IN KNOWLEDGE: This work supports feasibility of treating patients with metallic hip prosthesis on an MR Linac.
KW - MR Linac
KW - MR-guided radiotherapy
KW - Geometric distortion
KW - Metallic prosthesis
KW - Prostate radiotherapy
KW - Reproducibility of Results
KW - Radiotherapy Planning, Computer-Assisted/methods
KW - Humans
KW - Male
KW - Magnetic Resonance Imaging/methods
KW - Prostatic Neoplasms/diagnostic imaging
KW - Hip Prosthesis/adverse effects
KW - Phantoms, Imaging
KW - Particle Accelerators
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=pure_starter&SrcAuth=WosAPI&KeyUT=WOS:001177507800001&DestLinkType=FullRecord&DestApp=WOS_CPL
UR - https://www.mendeley.com/catalogue/c4633995-c407-3c59-a161-61a09100b2a4/
U2 - 10.1093/bjr/tqae044
DO - 10.1093/bjr/tqae044
M3 - Article
C2 - 38407369
SN - 0007-1285
VL - 97
SP - 757
EP - 762
JO - British Journal of Radiology
JF - British Journal of Radiology
IS - 1156
ER -
