Glyco-enzymatic cascades get protection

Kun Huang; Sabine L. Flitsch

doi:10.1038/s41929-019-0294-7

Glyco-enzymatic cascades get protection

Kun Huang, Sabine L. Flitsch^*

^*Corresponding author for this work

Research output: Contribution to journal › Commentary/debate › peer-review

Abstract

The biological functions of glycan motifs such as the Lewis blood antigens are often defined by their precise multivalent presentation on complex glycoconjugates, making synthesis particularly challenging. Access to a number of positionally defined Lewis motifs on natural polysaccharide scaffolds has now been achieved using bacterial glycosyltransferases.

Original language	English
Pages (from-to)	479-480
Number of pages	2
Journal	Nature Catalysis
Volume	2
Issue number	6
Early online date	13 Jun 2019
DOIs	https://doi.org/10.1038/s41929-019-0294-7
Publication status	Published - Jun 2019

Research Beacons, Institutes and Platforms

Manchester Institute of Biotechnology

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title = "Glyco-enzymatic cascades get protection",

abstract = "The biological functions of glycan motifs such as the Lewis blood antigens are often defined by their precise multivalent presentation on complex glycoconjugates, making synthesis particularly challenging. Access to a number of positionally defined Lewis motifs on natural polysaccharide scaffolds has now been achieved using bacterial glycosyltransferases.",

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Glyco-enzymatic cascades get protection

Abstract

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