Gold induced enterocolitis

C. W. Jackson, N. Y. Haboubi, P. J. Whorwell, P. F. Schofield

    Research output: Contribution to journalArticlepeer-review

    Abstract

    A case of gold associated enterocolitis is described. A review of all 27 previously reported cases revealed that the syndrome induced has common characteristics. The reaction occurs within three months of instituting gold therapy, is characterised by profuse diarrhoea and vomiting with abdominal pain, fever, and sometimes eosinophilia. Petechial changes are prominent on endoscopy and the endoscopic and histological features of the gut lesion do not resemble inflammatory bowel disease. The overall mortality is 26% but has decreased in recent years. There is no specific therapy but in severe cases diversional surgery may be justified.
    Original languageEnglish
    Pages (from-to)452-456
    Number of pages4
    JournalGut
    Volume27
    Issue number4
    Publication statusPublished - Apr 1986

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