Gynaecological cancer consists of five individual subsites: ovarian, endometrial, cervical, vaginal and vulval cancer. The proportion of older patients with frailty diagnosed with the different types of gynaecological cancer varies but in all subsites the number of these patients is increasing. Older age and frailty influence both the investigation and management of gynaecological cancers. In common with many other cancers, specific evidence to guide treatment in older patients with frailty is limited. This chapter will cover all five subsites of gynaecological cancer and provide a review of the evidence available for their management from early to advanced stages. Where this evidence is lacking, a frailty specific approach is taken, highlighting the potential benefits and limitations of standard treatments. Advances in systemic therapy, surgery and radiotherapy, which may particularly improve outcomes for patients with frailty are highlighted. The need for shared decision-making is emphasised throughout.
|Title of host publication||Frailty in Older Adults with Cancer|
|Number of pages||20|
|Publication status||Published - 15 Feb 2022|
Research Beacons, Institutes and Platforms
- Manchester Cancer Research Centre