HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea

R Yadav, M France, Reza Aghamohammadzadeh, Y Liu, S Hama, S Kwok, J Schofield, A Syed, Rayaz Malik, Paul Durrington, Adam Greenstein, Maria Jeziorska, Handrean Soran

Research output: Contribution to conferenceAbstract

Abstract

Objectives: Obstructive sleep apnea (OSA) is a common disorder in morbidly obese patients and is associated with the development of cardiovascular disease. Tumor necrosis factor α (TNFα), a mediator of vascular inflammation and paraoxonase 1 (PON1), an antioxidant enzyme associated with HDL have opposing effects, but have not been studied systematically in OSA.
Original languageEnglish
Pagese145
DOIs
Publication statusPublished - Aug 2014
Event82nd EAS Congress - Madrid
Duration: 31 May 20143 Jun 2014

Conference

Conference82nd EAS Congress
CityMadrid
Period31/05/143/06/14

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