HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea

R Yadav; M France; Reza Aghamohammadzadeh; Y Liu; S Hama; S Kwok; J Schofield; A Syed; Rayaz Malik; Paul Durrington; Adam Greenstein; Maria Jeziorska; Handrean Soran

doi:10.1016/j.atherosclerosis.2014.05.409

HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea

R Yadav, M France, Reza Aghamohammadzadeh, Y Liu, S Hama, S Kwok, J Schofield, A Syed, Rayaz Malik, Paul Durrington, Adam Greenstein, Maria Jeziorska, Handrean Soran

Research output: Contribution to conference › Abstract

Abstract

Objectives: Obstructive sleep apnea (OSA) is a common disorder in morbidly obese patients and is associated with the development of cardiovascular disease. Tumor necrosis factor α (TNFα), a mediator of vascular inflammation and paraoxonase 1 (PON1), an antioxidant enzyme associated with HDL have opposing effects, but have not been studied systematically in OSA.

Original language	English
Pages	e145
DOIs	https://doi.org/10.1016/j.atherosclerosis.2014.05.409
Publication status	Published - Aug 2014
Event	82nd EAS Congress - Madrid Duration: 31 May 2014 → 3 Jun 2014

Conference

Conference	82nd EAS Congress
City	Madrid
Period	31/05/14 → 3/06/14

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.atherosclerosis.2014.05.409

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Yadav, R., France, M., Aghamohammadzadeh, R., Liu, Y., Hama, S., Kwok, S., Schofield, J., Syed, A., Malik, R., Durrington, P., Greenstein, A., Jeziorska, M., & Soran, H. (2014). HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea. e145. Abstract from 82nd EAS Congress, Madrid. https://doi.org/10.1016/j.atherosclerosis.2014.05.409

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title = "HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea",

abstract = "Objectives: Obstructive sleep apnea (OSA) is a common disorder in morbidly obese patients and is associated with the development of cardiovascular disease. Tumor necrosis factor α (TNFα), a mediator of vascular inflammation and paraoxonase 1 (PON1), an antioxidant enzyme associated with HDL have opposing effects, but have not been studied systematically in OSA.",

author = "R Yadav and M France and Reza Aghamohammadzadeh and Y Liu and S Hama and S Kwok and J Schofield and A Syed and Rayaz Malik and Paul Durrington and Adam Greenstein and Maria Jeziorska and Handrean Soran",

year = "2014",

month = aug,

doi = "10.1016/j.atherosclerosis.2014.05.409",

language = "English",

pages = "e145",

note = "82nd EAS Congress ; Conference date: 31-05-2014 Through 03-06-2014",

}

Yadav, R, France, M, Aghamohammadzadeh, R, Liu, Y, Hama, S, Kwok, S, Schofield, J, Syed, A, Malik, R, Durrington, P, Greenstein, A , Jeziorska, M & Soran, H 2014, 'HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea', 82nd EAS Congress, Madrid, 31/05/14 - 3/06/14 pp. e145. https://doi.org/10.1016/j.atherosclerosis.2014.05.409

TY - CONF

T1 - HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea

AU - Yadav, R

AU - France, M

AU - Aghamohammadzadeh, Reza

AU - Liu, Y

AU - Hama, S

AU - Kwok, S

AU - Schofield, J

AU - Syed, A

AU - Malik, Rayaz

AU - Durrington, Paul

AU - Greenstein, Adam

AU - Jeziorska, Maria

AU - Soran, Handrean

PY - 2014/8

Y1 - 2014/8

N2 - Objectives: Obstructive sleep apnea (OSA) is a common disorder in morbidly obese patients and is associated with the development of cardiovascular disease. Tumor necrosis factor α (TNFα), a mediator of vascular inflammation and paraoxonase 1 (PON1), an antioxidant enzyme associated with HDL have opposing effects, but have not been studied systematically in OSA.

AB - Objectives: Obstructive sleep apnea (OSA) is a common disorder in morbidly obese patients and is associated with the development of cardiovascular disease. Tumor necrosis factor α (TNFα), a mediator of vascular inflammation and paraoxonase 1 (PON1), an antioxidant enzyme associated with HDL have opposing effects, but have not been studied systematically in OSA.

U2 - 10.1016/j.atherosclerosis.2014.05.409

DO - 10.1016/j.atherosclerosis.2014.05.409

M3 - Abstract

SP - e145

T2 - 82nd EAS Congress

Y2 - 31 May 2014 through 3 June 2014

ER -

HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea

Abstract

Conference

UN SDGs

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