Height, age at menarche, and risk of epithelial ovarian cancer

Susan J. Jordan; Penelope M. Webb; Adèle C. Green

doi:10.1158/1055-9965.EPI-05-0085

Height, age at menarche, and risk of epithelial ovarian cancer

Susan J. Jordan, Penelope M. Webb, Adèle C. Green

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: We hypothesized that the hormonal changes of adolescence influence ovarian cancer risk particularly in younger women. We investigated this possibility by examining the relationship between ovarian cancer and adult height and age at menarche as both factors reflect pubertal hormonal levels. Methods: Participants were a population-based sample of women with incident ovarian cancer (n = 794) and control women randomly selected from the Australian Electoral Roll (n = 855). The women provided comprehensive reproductive and lifestyle data during a standard interview. Results: Although neither height nor age at menarche was significantly related to the risk of ovarian cancer overall, increasing height was associated with increasing risk of the subgroup of mucinous borderline ovarian cancer (odds ratio, 5.3; 95% confidence interval, 1.5-19.1 for women ≥175 cm compared with women

Original language	English
Pages (from-to)	2045-2048
Number of pages	3
Journal	Cancer Epidemiology Biomarkers and Prevention
Volume	14
Issue number	8
DOIs	https://doi.org/10.1158/1055-9965.EPI-05-0085
Publication status	Published - Aug 2005

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10.1158/1055-9965.EPI-05-0085

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title = "Height, age at menarche, and risk of epithelial ovarian cancer",

abstract = "Objective: We hypothesized that the hormonal changes of adolescence influence ovarian cancer risk particularly in younger women. We investigated this possibility by examining the relationship between ovarian cancer and adult height and age at menarche as both factors reflect pubertal hormonal levels. Methods: Participants were a population-based sample of women with incident ovarian cancer (n = 794) and control women randomly selected from the Australian Electoral Roll (n = 855). The women provided comprehensive reproductive and lifestyle data during a standard interview. Results: Although neither height nor age at menarche was significantly related to the risk of ovarian cancer overall, increasing height was associated with increasing risk of the subgroup of mucinous borderline ovarian cancer (odds ratio, 5.3; 95% confidence interval, 1.5-19.1 for women ≥175 cm compared with women",

author = "Jordan, {Susan J.} and Webb, {Penelope M.} and Green, {Ad{\`e}le C.}",

year = "2005",

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doi = "10.1158/1055-9965.EPI-05-0085",

language = "English",

volume = "14",

pages = "2045--2048",

journal = "Cancer Epidemiology Biomarkers and Prevention",

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publisher = "American Association for Cancer Research",

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T1 - Height, age at menarche, and risk of epithelial ovarian cancer

AU - Jordan, Susan J.

AU - Webb, Penelope M.

AU - Green, Adèle C.

PY - 2005/8

Y1 - 2005/8

N2 - Objective: We hypothesized that the hormonal changes of adolescence influence ovarian cancer risk particularly in younger women. We investigated this possibility by examining the relationship between ovarian cancer and adult height and age at menarche as both factors reflect pubertal hormonal levels. Methods: Participants were a population-based sample of women with incident ovarian cancer (n = 794) and control women randomly selected from the Australian Electoral Roll (n = 855). The women provided comprehensive reproductive and lifestyle data during a standard interview. Results: Although neither height nor age at menarche was significantly related to the risk of ovarian cancer overall, increasing height was associated with increasing risk of the subgroup of mucinous borderline ovarian cancer (odds ratio, 5.3; 95% confidence interval, 1.5-19.1 for women ≥175 cm compared with women

AB - Objective: We hypothesized that the hormonal changes of adolescence influence ovarian cancer risk particularly in younger women. We investigated this possibility by examining the relationship between ovarian cancer and adult height and age at menarche as both factors reflect pubertal hormonal levels. Methods: Participants were a population-based sample of women with incident ovarian cancer (n = 794) and control women randomly selected from the Australian Electoral Roll (n = 855). The women provided comprehensive reproductive and lifestyle data during a standard interview. Results: Although neither height nor age at menarche was significantly related to the risk of ovarian cancer overall, increasing height was associated with increasing risk of the subgroup of mucinous borderline ovarian cancer (odds ratio, 5.3; 95% confidence interval, 1.5-19.1 for women ≥175 cm compared with women

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DO - 10.1158/1055-9965.EPI-05-0085

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SN - 1055-9965

VL - 14

SP - 2045

EP - 2048

JO - Cancer Epidemiology Biomarkers and Prevention

JF - Cancer Epidemiology Biomarkers and Prevention

IS - 8

ER -

Height, age at menarche, and risk of epithelial ovarian cancer

Abstract

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