Histological data of axons, astrocytes, and myelin in deep subcortical white matter populations

Santiago Coelho, Jose M. Pozo, Marina Costantini, J. Robin Highley, Meghdoot Mozumder, Julie E. Simpson, Paul G. Ince, Alejandro F. Frangi

Research output: Contribution to journalArticlepeer-review

Abstract

This immunohistochemistry dataset contains the main structures in deep subcortical white matter (axons, astrocytes, and myelinated axons) in a representative cohort of an ageing population. A set of samples from 90 subjects of the Cognitive Function and Ageing Study (CFAS) were analysed, stratified into three groups of 30 subjects each, in relation to the presence of age-associated deep subcortical lesions. High-resolution microscopy data enables the extraction of valuable information, such as volume fractions, for the construction and validation of diffusion MRI (dMRI) models. The dataset provided here was used in Coelho et al. [1].

Original languageEnglish
Article number103762
Pages (from-to)1-5
Number of pages5
JournalData in Brief
Volume23
DOIs
Publication statusPublished - Apr 2019

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