History of allergic disease and risk of meningioma

M. J. Schoemaker, A. J. Swerdlow, S. J. Hepworth, M. Van Tongeren, K. R. Muir, P. A. McKinney

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Epidemiologic studies have consistently shown inverse associations of allergic disease with risk of glioma, but it is unclear whether this association also applies to meningioma. The authors conducted a pooled analysis of meningioma risk in relation to a history of allergic disease based on data from two population-based, case-control studies with 475 cases and 1,716 controls in the United Kingdom (2001-2004). Meningioma risk was significantly reduced in relation to self-reported, physician-diagnosed allergic disease (odds ratio = 0.76, 95% confidence interval (CI): 0.61, 0.96) but was nonsignificantly reduced for individual conditions: asthma (odds ratio = 0.85, 95% CI: 0.61, 1.18), hay fever (odds ratio = 0.81, 95% CI: 0.62, 1.06), and eczema (odds ratio = 0.72, 95% CI: 0.51, 1.02). Risk reductions were greatest for asthma (odds ratio = 0.43, 95% CI: 0.21, 0.89) and hay fever (odds ratio = 0.50, 95% CI: 0.25, 1.00) with an early age at onset (
Original languageEnglish
Title of host publicationAmerican Journal of Epidemiology
Pages477-485
Number of pages9
Volume165
Edition5
DOIs
Publication statusPublished - Mar 2007

Publication series

NameAmerican Journal of Epidemiology
Volume165

Keywords

  • Allergy and immunology
  • Case-control studies
  • Meningioma

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