HLA-DR4 associated Dw types in rheumatoid arthritis

W. Ollier, D. Carthy, S. Cutbush, R. Okoye, J. Awad, A. Fielder, A. Silman, H. Festenstein

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Frequencies of HLA-DR4 and its related Dw types were compared between randomly selected normal controls and the index cases of multiplex rheumatoid arthritis (RA) families. A DR4 frequency of 68.3% was observed in index cases (n=57) compared to 31.2% in normal controls (n=96). Cellular typing with homozygous typing cells (HTCs) revealed significant increases of Dw4 (49.1% vs. 22.9% RR = 3.2 p
    Original languageEnglish
    Pages (from-to)30-37
    Number of pages7
    JournalTissue Antigens
    Volume33
    Issue number1
    Publication statusPublished - 1989

    Keywords

    • ACADEMIC JOURNAL PAPERS
    • ORIGINAL ARTICLES

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