How can NMR spectroscopy help protein biopharmaceutical development?

Nuclear magnetic resonance (NMR) spectroscopy is a technique that most have heard of but many avoid, especially when dealing with larger biological macromolecules. Why? The common wisdom is that NMR can be complicated, expensive and involves quantum physics and complex equations. In the fast-paced industrial biopharmaceutical environment there may be a disinclination to expend the necessary time and resources to set up the technique, but Jack Bramham and Alexander Golovanov highlight here some reasons why it may be worth the investment.