Human corticotropin releasing hormone gene is located on the long arm of chromosome 8

J L Arbiser, C C Morton, G A Bruns, J A Majzoub

Research output: Contribution to journalArticlepeer-review

Abstract

The chromosomal locus of the human corticotropin releasing hormone (hCRH) gene was assigned to chromosome 8 using Southern blot analysis of human x rodent cell hybrids and was localized to band 8q13 using in situ hybridization to metaphase chromosomes. The absence of secondary hybridization strongly suggests that hypothalamic and placental CRH are transcribed from the same gene.

Original languageEnglish
Pages (from-to)113-6
Number of pages4
JournalCytogenetics and Cell Genetics
Volume47
Issue number3
Publication statusPublished - 1988

Keywords

  • Animals
  • Chromosome Banding
  • Chromosome Mapping
  • Chromosomes, Human, Pair 8
  • Corticotropin-Releasing Hormone
  • Cricetinae
  • Cricetulus
  • DNA
  • Humans
  • Hybrid Cells
  • Karyotyping
  • Mice
  • Nucleic Acid Hybridization
  • Journal Article
  • Research Support, U.S. Gov't, P.H.S.

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