Abstract
The chromosomal locus of the human corticotropin releasing hormone (hCRH) gene was assigned to chromosome 8 using Southern blot analysis of human x rodent cell hybrids and was localized to band 8q13 using in situ hybridization to metaphase chromosomes. The absence of secondary hybridization strongly suggests that hypothalamic and placental CRH are transcribed from the same gene.
Original language | English |
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Pages (from-to) | 113-6 |
Number of pages | 4 |
Journal | Cytogenetics and Cell Genetics |
Volume | 47 |
Issue number | 3 |
Publication status | Published - 1988 |
Keywords
- Animals
- Chromosome Banding
- Chromosome Mapping
- Chromosomes, Human, Pair 8
- Corticotropin-Releasing Hormone
- Cricetinae
- Cricetulus
- DNA
- Humans
- Hybrid Cells
- Karyotyping
- Mice
- Nucleic Acid Hybridization
- Journal Article
- Research Support, U.S. Gov't, P.H.S.