Human pulmonary alveolar macrophages with smokers' inclusions: their relation to the cessation of cigarette smoking

R. M. Agius, A. Rutman, R. K. Knight, P. J. Cole

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Bronchoalveolar lavage (BAL) was performed in 47 patients (24 smokers, 18 ex-smokers and 5 who never smoked). Cytocentrifuged preparations were stained with May-Grunwald-Giemsa (MGG) and differential counts of pulmonary alveolar macrophages (PAM) with smokers' inclusions were performed. The data supported an exponential reduction in this percentage and indicated that about 3 years elapsed before this percentage approximated to the values in patients who had never smoked. Electron microscopy was performed on eight BALs and the results supported those obtained by light microscopy.
    Original languageEnglish
    Pages (from-to)407-413
    Number of pages6
    JournalBritish Journal of Experimental Pathology
    Volume67
    Issue number3
    Publication statusPublished - 1986

    Keywords

    • Adult
    • Aged
    • Cell Count
    • Female
    • Humans
    • Inclusion Bodies/ultrastructure
    • Macrophages/*ultrastructure
    • Male
    • Microscopy, Electron
    • Middle Aged
    • Pulmonary Alveoli/*ultrastructure
    • *Smoking
    • Time Factors

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